Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.
about
Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidanceThe RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activitiesThe interaction of DNA mismatch repair proteins with human exonuclease IWerner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activityHuman exonuclease I is required for 5' and 3' mismatch repairArginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determinationWRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication forkIdentification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2Essential amino acids for substrate binding and catalysis of human flap endonuclease 1Mini- and microsatellitesp21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complexA network of multi-tasking proteins at the DNA replication fork preserves genome stabilityThe crystal structure of flap endonuclease-1 from Methanococcus jannaschiiThe RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis.The MPH1 gene of Saccharomyces cerevisiae functions in Okazaki fragment processing.Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiaeAccumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.Molecular mechanism of base excision repair of uracil-containing DNA in yeast cell-free extractsA yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential functionEvidence for a role of FEN1 in maintaining mitochondrial DNA integrityInteractions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeastProcessing and joining of DNA ends coordinated by interactions among Dnl4/Lif1, Pol4, and FEN-1.DNA mismatch repair and mutation avoidance pathwaysProcessing of an HIV replication intermediate by the human DNA replication enzyme FEN1DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeThe protein components and mechanism of eukaryotic Okazaki fragment maturation.Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair.Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism.Shade avoidance 6 encodes an Arabidopsis flap endonuclease required for maintenance of genome integrity and developmentSchizosaccharomyces pombe MutSα and MutLα Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats.Eukaryotic Mismatch Repair in Relation to DNA ReplicationMapping the polarity of changes that occur in interrupted CAG repeat tracts in yeast.Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).Mutational spectrum analysis of RNase H(35) deficient Saccharomyces cerevisiae using fluorescence-based directed termination PCR.FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer.The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae.A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism.Novel function of Rad27 (FEN-1) in restricting short-sequence recombination.Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage
P2860
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P2860
Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Requirement of the yeast RTH1 ...... lity of simple repetitive DNA.
@en
type
label
Requirement of the yeast RTH1 ...... lity of simple repetitive DNA.
@en
prefLabel
Requirement of the yeast RTH1 ...... lity of simple repetitive DNA.
@en
P2093
P356
P1433
P1476
Requirement of the yeast RTH1 ...... lity of simple repetitive DNA.
@en
P2093
G K Kovvali
R E Johnson
P304
P356
10.1126/SCIENCE.7618086
P407
P577
1995-07-01T00:00:00Z