1,4-Thienodiazepine-2,5-diones via MCR (I): synthesis, virtual space and p53-Mdm2 activity.
about
Chemical Variations on the p53 Reactivation ThemeExhaustive Fluorine Scanning toward Potent p53-Mdm2 Antagonists1,4-Thienodiazepine-2,5-diones via MCR (II): scaffold hopping by Gewald and Ugi-deprotection-cyclization strategyPrivileged diazepine compounds and their emergence as bromodomain inhibitors.P53 mdm2 inhibitors.EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.Fragment-based library generation for the discovery of a peptidomimetic p53-Mdm4 inhibitorProtozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.General one-pot, two-step protocol accessing a range of novel polycyclic heterocycles with high skeletal diversityChemistry and biology of multicomponent reactions.Benzimidazole-2-one: a novel anchoring principle for antagonizing p53-Mdm2Discovery of highly potent p53-MDM2 antagonists and structural basis for anti-acute myeloid leukemia activities.Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics.Targeting p53-MDM2-MDMX loop for cancer therapy.Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods.Multicomponent synthesis of diverse 1,4-benzodiazepine scaffolds.Concise Synthesis of Tetrazole MacrocycleArtificial Macrocycles as Potent p53-MDM2 Inhibitors.Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation
P2860
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P2860
1,4-Thienodiazepine-2,5-diones via MCR (I): synthesis, virtual space and p53-Mdm2 activity.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
1,4-Thienodiazepine-2,5-diones ...... l space and p53-Mdm2 activity.
@en
type
label
1,4-Thienodiazepine-2,5-diones ...... l space and p53-Mdm2 activity.
@en
prefLabel
1,4-Thienodiazepine-2,5-diones ...... l space and p53-Mdm2 activity.
@en
P2093
P2860
P50
P1476
1,4-Thienodiazepine-2,5-diones ...... al space and p53-Mdm2 activity
@en
P2093
Carlos Camacho
Lidio Meireles
Siglinde Wolf
Tad A Holak
Yijun Huang
P2860
P304
P356
10.1111/J.1747-0285.2010.00989.X
P577
2010-05-18T00:00:00Z