Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis. - Wikidata - awgldk - TriplyDB

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

http://www.wikidata.org/entity/Q42957359

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The emerging role of pituitary tumor transforming gene in tumorigenesis PTTG1 attenuates drug-induced cellular senescence Direct promoter induction of p19Arf by Pit-1 explains the dependence receptor RET/Pit-1/p53-induced apoptosis in the pituitary somatotroph cells Pituitary gland development and disease: from stem cell to hormone production Pituitary tumor transforming gene-1 haplotypes and risk of pituitary adenoma: a case-control study.Mitotic chromosomal instability and cancer: mouse modelling of the human disease.Genetically engineered mouse models of pituitary tumors Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.Antidepressants stimulate hippocampal neurogenesis by inhibiting p21 expression in the subgranular zone of the hipppocampus.p21Cip restrains hippocampal neurogenesis and protects neuronal progenitors from apoptosis during acute systemic inflammation.Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.Inhibition of pituitary tumor-transforming gene-1 in thyroid cancer cells by drugs that decrease specificity proteins Correlations of pituitary tumor transforming gene expression with human pituitary adenomas: a meta-analysis.Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin.Lhx4 deficiency: increased cyclin-dependent kinase inhibitor expression and pituitary hypoplasia.PTTG expression in different experimental and human prolactinomas in relation to dopaminergic control of lactotropes.Aneuploidy and chromosomal instability in cancer: a jackpot to chaos.p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis.PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma.Estradiol partially recapitulates murine pituitary cell cycle response to pregnancy.p21Cip1 restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus Clusterin and FOXL2 act concordantly to regulate pituitary gonadotroph adenoma growth Animal models of pituitary neoplasia Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.Aneuploidy in health, disease, and aging.p21(Cip1) restrains pituitary tumor growth.PTTG: an important target gene for ovarian cancer therapy.Whole chromosome instability and cancer: a complex relationship High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation.2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis Key signaling molecules in pituitary tumors.Pituitary senescence: the evolving role of Pttg.Pituitary tumor-transforming gene and its binding factor in endocrine cancer.Genetic instability: tipping the balance.The cancer biology of whole-chromosome instability.

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Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

http://www.wikidata.org/entity/Q42957359

description

2005 nî lūn-bûn

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2005年の論文

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name

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

@en

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

@nl

type

label

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

@en

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

@nl

prefLabel

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

@en

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

@nl

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Molecular Endocrinology

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Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

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Anna-Valeria Castro

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Kalman Kovacs

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Shlomo Melmed

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Svetlana Zonis

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Vera Chesnokova

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P2860

The Hallmarks of Cancer

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

CDK inhibitors: positive and negative regulators of G1-phase progression

Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

Human pituitary tumor-transforming gene induces angiogenesis

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

Cancer-susceptibility genes. Gatekeepers and caretakers

From polyploidy to aneuploidy, genome instability and cancer

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

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2371-2379

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10.1210/ME.2005-0137

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19

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7821581

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