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Induced pluripotent stem cell technology for dissecting the cancer epigenomeChromatin targeting drugs in cancer and immunityChemogenetic analysis of human protein methyltransferasesEpigenetics in Intestinal Epithelial Cell RenewalDevelopment of New Molecular EZH2 on Lung Cancer Invasion and MetastasisPRC2/EED-EZH2 complex is up-regulated in breast cancer lymph node metastasis compared to primary tumor and correlates with tumor proliferation in situIdentification of somatic mutations in parathyroid tumors using whole-exome sequencingJMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity.EZH2 depletion blocks the proliferation of colon cancer cells.Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas.The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism.The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinomaCancer epigenetics: above and beyondPolycomb repressive complex 2 is required for MLL-AF9 leukemiaEpigenetic mechanisms in virus-induced tumorigenesis.The Third Intron of the Interferon Regulatory Factor-8 Is an Initiator of Repressed Chromatin Restricting Its Expression in Non-Immune CellsIntegrative genome-wide approaches in embryonic stem cell research.Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokinesQuantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell linesQuantitative proteomics reveals histone modifications in crosstalk with H3 lysine 27 methylation.The tumor suppressor role of CTCF.Histone onco-modifications.Epigenomics in hematopoietic transplantation: novel treatment strategies.Epigenetics: Concepts and relevance to IBD pathogenesis.The methylation landscape of tumour metastasis.Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail.Detection of driver and subclonal mutations in myelofibrosis: clinical impact on pharmacologic and transplant based treatment strategies.ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.Prognosis of Primary Myelofibrosis in the Genomic EraLoss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies.Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine GliomaThe roles of epigenetic modifications of proapoptotic BID and BIM genes in imatinib-resistant chronic myeloid leukemia cells.Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer.Vitamin D has wide regulatory effects on histone demethylase genes.Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma.3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Deregulation of H3K27 methylation in cancer.
@en
Deregulation of H3K27 methylation in cancer.
@nl
type
label
Deregulation of H3K27 methylation in cancer.
@en
Deregulation of H3K27 methylation in cancer.
@nl
prefLabel
Deregulation of H3K27 methylation in cancer.
@en
Deregulation of H3K27 methylation in cancer.
@nl
P2860
P356
P1433
P1476
Deregulation of H3K27 methylation in cancer.
@en
P2093
Eva Martinez-Garcia
P2860
P2888
P304
P356
10.1038/NG0210-100
P407
P577
2010-02-01T00:00:00Z
P5875
P6179
1049824727