Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
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Strong cooperativity between subunits in voltage-gated proton channelsFunctionality of the voltage-gated proton channel truncated in S4Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channelsOutward Rectification of Voltage-Gated K+ Channels Evolved at Least Twice in Life HistoryHyperpolarization moves S4 sensors inward to open MVP, a methanococcal voltage-gated potassium channelCellular processing of cone photoreceptor cyclic GMP-gated ion channels: a role for the S4 structural motifIdentification of putative potassium channel homologues in pathogenic protozoaIdentification and analysis of cation channel homologues in human pathogenic fungiRestoration of proper trafficking to the cell surface for membrane proteins harboring cysteine mutationsThe VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic HomeostasisPhylogeny as a guide to structure and function of membrane transport proteins.How is the heart rate regulated in the sinoatrial node? Another piece to the puzzleChemical tools for K(+) channel biology.P-loop residues critical for selectivity in K channels fail to confer selectivity to rabbit HCN4 channels.Reversed voltage-dependent gating of a bacterial sodium channel with proline substitutions in the S6 transmembrane segment.Helical secondary structure of the external S3-S4 linker of pacemaker (HCN) channels revealed by site-dependent perturbations of activation phenotype.Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.Molecular mechanism underlying phosphatidylinositol 4,5-bisphosphate-induced inhibition of SpIH channels.The search is on for the voltage sensor-to-gate coupling.Modular thermal sensors in temperature-gated transient receptor potential (TRP) channelscAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.Functional Characterization of Cnidarian HCN Channels Points to an Early Evolution of Ih.Nav channel mechanosensitivity: activation and inactivation accelerate reversibly with stretch.Inner activation gate in S6 contributes to the state-dependent binding of cAMP in full-length HCN2 channel.The Role of HCN Channels on Membrane Excitability in the Nervous SystemStructural changes during HCN channel gating defined by high affinity metal bridges.Molecular template for a voltage sensor in a novel K+ channel. I. Identification and functional characterization of KvLm, a voltage-gated K+ channel from Listeria monocytogenes.Molecular template for a voltage sensor in a novel K+ channel. II. Conservation of a eukaryotic sensor fold in a prokaryotic K+ channel.Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6.Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels.Kinetic relationship between the voltage sensor and the activation gate in spHCN channelsThe zinc binding site of the Shaker channel KDC1 from Daucus carotaKCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channelsCharge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate.S4 movement in a mammalian HCN channel.Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels.Molecular coupling between voltage sensor and pore opening in the Arabidopsis inward rectifier K+ channel KAT1.A cyclic nucleotide modulated prokaryotic K+ channel.Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker propertiesFree-energy relationships in ion channels activated by voltage and ligand.
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Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
@en
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
@nl
type
label
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
@en
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
@nl
prefLabel
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
@en
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
@nl
P2860
P356
P1433
P1476
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages
@en
P2093
H Peter Larsson
P2860
P2888
P304
P356
10.1038/NATURE01038
P407
P577
2002-10-01T00:00:00Z
P6179
1003168560