Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
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The aldehyde oxidase gene cluster in mice and rats. Aldehyde oxidase homologue 3, a novel member of the molybdo-flavoenzyme family with selective expression in the olfactory mucosa.The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5.Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions.Human liver aldehyde oxidase: inhibition by 239 drugs.The mammalian aldehyde oxidase gene family.Involvement of enzymes other than CYPs in the oxidative metabolism of xenobiotics.Evaluation of the metabolism and hepatotoxicity of xenobiotics utilizing precision-cut slices.Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics.Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver.Novel pre-clinical methodologies for pharmacokinetic drug-drug interaction studies: spotlight on "humanized" animal models.Prevalence of Non-Cytochrome P450-Mediated Metabolism in Food and Drug Administration-Approved Oral and Intravenous Drugs: 2006-2015.Reductive half-reaction of aldehyde oxidoreductase toward acetaldehyde: Ab initio and free energy quantum mechanical/molecular mechanical calculations.Structure-based investigation of rat aldehyde oxidase inhibition by flavonoids.Inhibition of zaleplon metabolism by cimetidine in the human liver: in vitro studies with subcellular fractions and precision-cut liver slices.Identification of a suitable and selective inhibitor towards aldehyde oxidase catalyzed reactions.Species differences in metabolism of ripasudil (K-115) are attributed to aldehyde oxidase.Clinical risks of St John's Wort (Hypericum perforatum) co-administration.Direct comparison of the four aldehyde oxidase enzymes present in mouse gives insight into their substrate specificities.Inhibitory effects of flavonoids on aldehyde oxidase activityReversed–Phase Liquid Chromatographic Determination of Zaleplon in Human Plasma and its Pharmacokinetic Application
P2860
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P2860
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
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2002年學術文章
@zh-hant
name
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
@en
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
@nl
type
label
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
@en
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
@nl
prefLabel
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
@en
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
@nl
P2093
P2860
P1433
P1476
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase.
@en
P2093
P2860
P304
P356
10.1080/00498250210158915
P407
P577
2002-10-01T00:00:00Z