Analysis of transmembrane domain 2 of rat serotonin transporter by cysteine scanning mutagenesis.
about
Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporterModeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologueOligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix IIRecognition of psychostimulants, antidepressants, and other inhibitors of synaptic neurotransmitter uptake by the plasma membrane monoamine transportersCysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformationThe substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter.Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesisReconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue.Cytoplasmic permeation pathway of neurotransmitter transporters.Involvement of serotonin transporter extracellular loop 1 in serotonin binding and transport.Identification of a chloride ion binding site in Na+/Cl -dependent transporters.Helix XI contributes to the entrance of the serotonin transporter permeation pathway.Control of serotonin transporter phosphorylation by conformational state.The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle.Importance of the Extracellular Loop 4 in the Human Serotonin Transporter for Inhibitor Binding and Substrate Translocation.Channel domain of colicin A modifies the dimeric organization of its immunity protein.Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes.Study of polytopic membrane protein topological organization as a function of membrane lipid composition.A dualistic conformational response to substrate binding in the human serotonin transporter reveals a high affinity state for serotonin.Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis.Ibogaine, a noncompetitive inhibitor of serotonin transport, acts by stabilizing the cytoplasm-facing state of the transporter.The cytoplasmic substrate permeation pathway of serotonin transporter.
P2860
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P2860
Analysis of transmembrane domain 2 of rat serotonin transporter by cysteine scanning mutagenesis.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Analysis of transmembrane doma ...... cysteine scanning mutagenesis.
@en
Analysis of transmembrane doma ...... cysteine scanning mutagenesis.
@nl
type
label
Analysis of transmembrane doma ...... cysteine scanning mutagenesis.
@en
Analysis of transmembrane doma ...... cysteine scanning mutagenesis.
@nl
prefLabel
Analysis of transmembrane doma ...... cysteine scanning mutagenesis.
@en
Analysis of transmembrane doma ...... cysteine scanning mutagenesis.
@nl
P2093
P2860
P356
P1476
Analysis of transmembrane doma ...... cysteine scanning mutagenesis.
@en
P2093
Andreas Androutsellis-Theotokis
Gary Rudnick
Yuan-Wei Zhang
Yuichiro Sato
P2860
P304
22926-22933
P356
10.1074/JBC.M312194200
P407
P577
2004-03-25T00:00:00Z