CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45.
about
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forksIsolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicaseA requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replicationDNA binding and helicase actions of mouse MCM4/6/7 helicase.Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and FunctionArchitectures of archaeal GINS complexes, essential DNA replication initiation factorsCell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins.Interactions of MCP1 with components of the replication machinery in mammalian cells.Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakageUnscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage.Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA.Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progressionCell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy.The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpointInteractions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase.Cdc45-MCM-GINS, a new power player for DNA replication.Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins.Eukaryotic MCM proteins: beyond replication initiation.Cdc45 is limiting for replication initiation in humansA novel ring-like complex of Xenopus proteins essential for the initiation of DNA replicationCDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication.Plx1 is required for chromosomal DNA replication under stressful conditionsCell cycle regulation of DNA replication.Structure of human Cdc45 and implications for CMG helicase functionReplication initiation complex formation in the absence of nuclear function in Xenopus.The Mcm complex: unwinding the mechanism of a replicative helicase.ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes.The c-myc DNA-unwinding element-binding protein modulates the assembly of DNA replication complexes in vitro.Mechanisms and regulation of DNA replication initiation in eukaryotes.A novel intermediate in initiation complex assembly for fission yeast DNA replication.Centrosomal localization of cyclin E-Cdk2 is required for initiation of DNA synthesis.Regulation of DNA replication machinery by Mrc1 in fission yeast.The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy.
P2860
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P2860
CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
CDK- and Cdc45-dependent primi ...... ase by association with Cdc45.
@en
CDK- and Cdc45-dependent primi ...... ase by association with Cdc45.
@nl
type
label
CDK- and Cdc45-dependent primi ...... ase by association with Cdc45.
@en
CDK- and Cdc45-dependent primi ...... ase by association with Cdc45.
@nl
prefLabel
CDK- and Cdc45-dependent primi ...... ase by association with Cdc45.
@en
CDK- and Cdc45-dependent primi ...... ase by association with Cdc45.
@nl
P2093
P2860
P1433
P1476
CDK- and Cdc45-dependent primi ...... ase by association with Cdc45.
@en
P2093
Haruhiko Takisawa
Satoru Mimura
Taro Masuda
P2860
P304
P356
10.1046/J.1365-2443.2003.00621.X
P577
2003-02-01T00:00:00Z