DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.
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NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycleInhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylationRunt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivityWerner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distributionCell density-dependent acetylation of ΔNp63α is associated with p53-dependent cell cycle arresthSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damageSSRP1 functions as a co-activator of the transcriptional activator p63Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatinp53 acetylation is crucial for its transcription-independent proapoptotic functionsOncogenic Intra-p53 Family Member Interactions in Human CancersDNA repair and aging: the impact of the p53 familyStructure and apoptotic function of p73Protein lysine acetylation by p300/CBPStructure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitorIdentification and characterization of the cytoplasmic protein TRAF4 as a p53-regulated proapoptotic geneBID regulation by p53 contributes to chemosensitivityInactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-AblDevelopmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient miceTP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells.Targeting of p53-transcriptional dysfunction by conditionally replicating adenovirus is not limited by p53-homologues.Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells.Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth.The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.Multiple stress signals induce p73beta accumulation.The p53 homologue p73 accumulates in the nucleus and localizes to neurites and neurofibrillary tangles in Alzheimer disease brain.α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73.p73 in Cancer.A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage.Epigenomics and ovarian carcinoma.Nonhistone protein acetylation as cancer therapy targets.The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53.DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosisRegulation of p73 activity by post-translational modifications.Graft-versus-host disease-related cytokine-driven apoptosis depends on p73 in cytokeratin 15-positive target cellsA role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instabilityTumour suppressor genes in chemotherapeutic drug response.
P2860
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P2860
DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
DNA damage-dependent acetylati ...... ion of apoptotic target genes.
@en
DNA damage-dependent acetylati ...... ion of apoptotic target genes.
@nl
type
label
DNA damage-dependent acetylati ...... ion of apoptotic target genes.
@en
DNA damage-dependent acetylati ...... ion of apoptotic target genes.
@nl
prefLabel
DNA damage-dependent acetylati ...... ion of apoptotic target genes.
@en
DNA damage-dependent acetylati ...... ion of apoptotic target genes.
@nl
P2093
P50
P1433
P1476
DNA damage-dependent acetylati ...... tion of apoptotic target genes
@en
P2093
Clara Balsano
Giovanni Blandino
Louis Schiltz
Marcella Fulco
Maurizio Fanciulli
Natalia Pediconi
Philip A Cole
P304
P356
10.1016/S1097-2765(02)00431-8
P577
2002-01-01T00:00:00Z