Regulation of murine cystic fibrosis transmembrane conductance regulator Cl- channels expressed in Chinese hamster ovary cells.
about
A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactionsAirway hydration and COPDImpact of the F508del mutation on ovine CFTR, a Cl- channel with enhanced conductance and ATP-dependent gating.Folding and rescue of a cystic fibrosis transmembrane conductance regulator trafficking mutant identified using human-murine chimeric proteinsThe H-loop in the second nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator is required for efficient chloride channel closingEffects of serine/threonine protein phosphatases on ion channels in excitable membranes.Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms.Human-mouse cystic fibrosis transmembrane conductance regulator (CFTR) chimeras identify regions that partially rescue CFTR-ΔF508 processing and alter its gating defect.Bioelectric properties of chloride channels in human, pig, ferret, and mouse airway epithelia.Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTRMurine and human CFTR exhibit different sensitivities to CFTR potentiators.Voltage-dependent gating of the cystic fibrosis transmembrane conductance regulator Cl- channel.Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator.Front-runners for pharmacotherapeutic correction of the airway ion transport defect in cystic fibrosis.State-dependent modulation of CFTR gating by pyrophosphate.Acute inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel by thyroid hormones involves multiple mechanisms.CFTR potentiators partially restore channel function to A561E-CFTR, a cystic fibrosis mutant with a similar mechanism of dysfunction as F508del-CFTRRevertant mutants modify, but do not rescue, the gating defect of the cystic fibrosis mutant G551D-CFTR.Recovery of ΔF508-CFTR function by analogs of hyaluronan disaccharide.Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1.Increased efficacy of VX-809 in different cellular systems results from an early stabilization effect of F508del-CFTR.Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line.The two halves of CFTR form a dual-pore ion channel.Hematopoietic stem/progenitor cells express functional mitochondrial energy-dependent cystic fibrosis transmembrane conductance regulator.Role of protein phosphatases in the activation of CFTR (ABCC7) by genistein and bromotetramisole.State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator.Determination of the functional unit of the cystic fibrosis transmembrane conductance regulator chloride channel. One polypeptide forms one pore.Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule.
P2860
Q24311225-FEB0EC3C-70AB-45D7-8D08-6CBA82BA14AAQ28082617-5F385290-832C-4B86-B934-AC9AB09FECACQ30372632-8BF86719-12A4-4CED-BB83-DC70BEB7F4FEQ33605591-D6B0A4FE-AA92-4147-ACC8-510EE0469776Q33750252-0D13C31C-CE45-46D3-B738-BC5B0373B9C0Q33807200-732A87CF-B1C8-4051-BAA4-B39BBEA91744Q35215090-FA495A2C-8C1A-47A0-98C2-1031040B272BQ35734877-A00F58A0-A840-49EC-BA45-50507B650AAEQ35847294-0FCD7AA8-448D-4DD8-B086-63DD6BDC32CBQ36092657-D4EE132B-FA9A-4717-A106-DFFF7D3D818CQ36122891-A7CA1A9A-2981-46FE-A3F9-8E08BA04A0F4Q36436627-8EAB8EEF-645A-4156-9E18-8EB5B0F79197Q36510038-561D6FBD-E449-4459-9E59-888B40037872Q37158668-232A51E9-EAB9-4195-96F8-0306FCCFEB30Q37234233-E90F38DB-6A8C-482F-B0B2-4157BF42B23CQ37234590-D1F3053F-C814-44BB-BC07-85AFFE3D5EB3Q38987933-0294F88E-D513-471A-B94F-9FCDF78728C2Q39018857-12F5F853-763B-4591-9D6D-37C6E7CDDBF8Q39481242-46CF97D2-4B71-413E-B562-2A3F08F5E531Q39880519-FA4814CF-6282-41C0-9B2A-4AC5486F8E8DQ40741189-885E9FB0-73C5-4EDA-BE6A-5FA5797EEE47Q40886609-40D7C01D-36D4-4283-ADD8-C5EA27AA8F74Q40890137-8DFFE6C8-0B03-4649-A7BB-E195CA82EDCCQ41168425-5371C056-67DE-4D97-9989-3CCE44DF6653Q42490709-254F855E-D81A-4BFB-A2DD-123A48919D24Q42670820-D8AD74CF-F701-4A66-A384-57D2E644104FQ45124216-9322974B-FA89-45D7-B5FA-E2D83D5E8333Q47214928-A491C468-40DF-42F2-89E9-8B3421293F93
P2860
Regulation of murine cystic fibrosis transmembrane conductance regulator Cl- channels expressed in Chinese hamster ovary cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Regulation of murine cystic fi ...... n Chinese hamster ovary cells.
@en
Regulation of murine cystic fi ...... n Chinese hamster ovary cells.
@nl
type
label
Regulation of murine cystic fi ...... n Chinese hamster ovary cells.
@en
Regulation of murine cystic fi ...... n Chinese hamster ovary cells.
@nl
prefLabel
Regulation of murine cystic fi ...... n Chinese hamster ovary cells.
@en
Regulation of murine cystic fi ...... n Chinese hamster ovary cells.
@nl
P2093
P2860
P1476
Regulation of murine cystic fi ...... n Chinese hamster ovary cells.
@en
P2093
B J Wainwright
D N Sheppard
K A Lansdell
S J Delaney
P2860
P304
P356
10.1111/J.1469-7793.1998.751BD.X
P407
P478
512 ( Pt 3)
P577
1998-11-01T00:00:00Z