The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2
about
Cullin-RING ubiquitin ligases: global regulation and activation cyclesATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligaseFBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activityStructural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationE2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationSCCRO (DCUN1D1) is an essential component of the E3 complex for neddylationAn intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaBTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligaseDiversity of degradation signals in the ubiquitin-proteasome systemActivation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complexThe Ubiquitin System and Jasmonate SignalingThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyBuilding and remodelling Cullin-RING E3 ubiquitin ligasesGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesStructural basis for the function of DCN-1 in protein NeddylationA Dual E3 Mechanism for Rub1 Ligation to Cdc53Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceA RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligasesA role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.Elongin from Saccharomyces cerevisiae.The APC11 RING-H2 finger mediates E2-dependent ubiquitination.A longevity protein, Lag2, interacts with SCF complex and regulates SCF functionF-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat.Ubiquitylation, neddylation and the DNA damage responseFunction and regulation of cullin-RING ubiquitin ligasesThe conserved RING-H2 finger of ROC1 is required for ubiquitin ligationThe Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullinsDEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1Substrate-mediated regulation of cullin neddylationThe NEDD8 system is essential for cell cycle progression and morphogenetic pathway in miceEvolution and function of ubiquitin-like protein-conjugation systemsInactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesisRegulation of the G1 to S transition by the ubiquitin pathway.AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response.
P2860
Q21203558-AD9241A0-4755-4A77-9C5E-76752421A6F3Q24290903-AA723D1B-D26D-4801-98A0-2F4E8B324FE8Q24314409-02269F6B-66CB-43DC-A707-8261C0F7DAFDQ24314520-B00B988C-2A5C-4F4B-B2D9-7E4EBD7CEBECQ24316067-2A331F2E-BB87-4330-87DE-95589303EDEBQ24317319-8512C327-B31B-481A-8A22-B2974A42B89FQ24522556-9D8CFE81-7AB1-499F-BC46-FA883B5E4F02Q24529121-FE572ECA-8CCB-4F70-B4E8-3A6E02A02A1AQ24538586-8DF2604B-201C-49A4-8C67-88BF8959EBEAQ24551152-14556E7C-CFBA-4EAD-9C41-E41A31AD1C8FQ24554289-1EB12D64-0D34-4333-990D-10922CC613FBQ24558689-93D0DC9F-11FC-4D46-924D-783ECCE052C7Q24642979-8C2EE1B4-CD8B-4F23-BAE9-9B263FB68BCBQ24655274-75D5E26F-E880-4195-9780-4A7EC562A471Q26748467-16619654-B2B2-486E-B438-CE80BE8A2195Q26782011-5FEE4DB4-6AFD-47F3-84D7-2C758FD1DD9BQ27003218-B002FA1D-4FBE-4C3D-9BF7-8844424BE75FQ27027816-28A414F4-399A-4A14-A891-FA34ACBE2130Q27027897-E93D30F4-72B4-4F91-916C-7294D0D7B6CBQ27646469-3E2E4342-6851-4809-B9B9-08247610D52DQ27664416-EAC75505-96C3-42AE-B127-5E150B1B70E7Q27670574-38B21E46-99CB-432A-930F-86E920195F9EQ27670841-49EBEEFC-1266-476F-9B79-63A22400AA74Q27931729-0AB11FE6-F21E-4AC4-A18D-9DC214DCED3EQ27934153-B55DD65A-1E42-4426-9119-201DD24E219CQ27934826-C2D1EE8E-F8F5-402A-A474-EBD55D593DA2Q27934969-7A6C1088-701C-4695-979B-4E24AD359EBAQ27939951-87C997D3-8803-4A52-9286-3F917E05F6D4Q28087342-4E5714EE-6BDA-47BF-9386-EB9C63302FB1Q28131707-22716DC2-4FF8-4F0A-BEE8-B065B882D1CBQ28140666-91AE923D-489E-4144-81C7-E676E68507EAQ28201996-A1D7F1F2-B585-47E1-BBEA-FAAB4947330BQ28203487-F4136DA5-9788-4F4C-9094-813EA426290EQ28205415-B16F95B2-6E16-445B-835C-9540D37AA81EQ28298285-57C4A68B-7589-48F0-AD10-D80724ABA8C2Q28592951-3DE106A4-4864-4AEE-A25D-F879B2F4FA72Q30004192-4C09D766-7FB2-4E49-9B6A-B28C3C6C6D40Q30569769-25E64317-A155-4FF0-9319-B47FF7825CF3Q32062435-A011EB32-73A8-4BF6-97A3-94FA72C483EDQ33336974-B2987952-0159-4697-827E-D239FC0ACD1E
P2860
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@ast
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@en
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@nl
type
label
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@ast
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@en
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@nl
prefLabel
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@ast
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@en
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@nl
P2093
P2860
P356
P1433
P1476
The Rbx1 subunit of SCF and VH ...... tion of cullins Cdc53 and Cul2
@en
P2093
J W Conaway
M N Conrad
R C Conaway
P2860
P304
P356
10.1101/GAD.13.22.2928
P407
P50
P577
1999-11-15T00:00:00Z