Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
about
DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formationTRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodiesParkin ubiquitinates and promotes the degradation of RanBP2Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagyParkin mono-ubiquitinates Bcl-2 and regulates autophagyThe p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosisAutoregulation of Parkin activity through its ubiquitin-like domainParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7Ataxin-3 is a multivalent ligand for the parkin Ubl domainHow does parkin ligate ubiquitin to Parkinson's disease?Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype.The ubiquitin proteasome system in neuropathologyParkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channelsSensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary ParkinsonismParkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicityParkin Regulation and Neurodegenerative DisordersUbiquitin-dependent trafficking and turnover of ionotropic glutamate receptorsThe associations between Parkinson's disease and cancer: the plot thickensRBR E3 ubiquitin ligases: new structures, new insights, new questionsMolecular aspects of dopaminergic neurodegeneration: gene-environment interaction in parkin dysfunctionPathologic and therapeutic implications for the cell biology of parkinCell-permeable parkin proteins suppress Parkinson disease-associated phenotypes in cultured cells and animalsInsights into the key roles of proteoglycans in breast cancer biology and translational medicineFunction and regulation of cullin-RING ubiquitin ligasesParkin is protective against proteotoxic stress in a transgenic zebrafish modelIdentification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysisAnkyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's diseaseParkin occurs in a stable, non-covalent, approximately 110-kDa complex in brainPruning and loss of excitatory synapses by the parkin ubiquitin ligaseLoss of locus coeruleus neurons and reduced startle in parkin null mice.Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by ParkinMPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.Ubiquitin domain proteins in disease.Role of the ubiquitin proteasome system in Parkinson's disease.The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxiasBridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity.Parkin-mediated ubiquitination regulates phospholipase C-gamma1.Mechanisms of Parkinson's disease-related proteins in mediating secondary brain damage after cerebral ischemia.FBXL21 association with schizophrenia in Irish family and case-control samples.
P2860
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P248
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P2860
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@ast
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@en
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@en-gb
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@nl
type
label
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@ast
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@en
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@en-gb
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@nl
prefLabel
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@ast
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@en
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@en-gb
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@nl
P2093
P921
P1433
P1476
Parkin is a component of an SC ...... ns from kainate excitotoxicity
@en
P2093
Asa Abeliovich
Brenda Schulman
Caroline McDermott
Cécile Martinat
Elena Demireva
John F Staropoli
P304
P356
10.1016/S0896-6273(03)00084-9
P407
P577
2003-03-06T00:00:00Z