MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.
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Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsGene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian modelsResistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activationValue of genetic models in understanding the cause and mechanisms of Parkinson's diseaseAnimal models of Parkinson's disease: vertebrate geneticsNeuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.A comprehensive analysis of the effect of DSP4 on the locus coeruleus noradrenergic system in the ratMitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis.Identification and characterization of a novel endogenous murine parkin mutation.Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's diseasePrenatal LPS increases inflammation in the substantia nigra of Gdnf heterozygous miceMitochondrial dysfunction in genetic animal models of Parkinson's diseaseMitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease.Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.Parkin deficiency increases vulnerability to inflammation-related nigral degenerationS-nitrosylation of XIAP compromises neuronal survival in Parkinson's diseaseConditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons.Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.The role of parkin in familial and sporadic Parkinson's disease.Genetic animal models of Parkinson's disease.Genetic mutations and mitochondrial toxins shed new light on the pathogenesis of Parkinson's disease.Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.Limbic system pathologies associated with deficiencies and excesses of the trace elements iron, zinc, copper, and selenium.Functional Role of Parkin against Oxidative Stress in Neural Cells.Neurotoxin-induced DNA damage is persistent in SH-SY5Y cells and LC neurons.Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio).High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts.Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease.Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.Lack of long-term changes in circadian, locomotor, and cognitive functions in acute and chronic MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse models of Parkinson's disease.α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism.Parkin-knockout mice did not display increased vulnerability to intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).Current perspective of mitochondrial biology in Parkinson's disease.Comparative analysis of Parkinson's disease-associated genes reveals altered survival and bioenergetics of parkin-deficient dopamine neurons in mice.Zebrafish as an Animal Model for Drug Discovery in Parkinson's Disease and Other Movement Disorders: A Systematic Review.PICK1 inhibits the E3 ubiquitin ligase activity of Parkin and reduces its neuronal protective effectInvestigation of Behavioral Dysfunctions Induced by Monoamine Depletions in a Mouse Model of Parkinson's Disease
P2860
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P2860
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
MPTP and DSP-4 susceptibility ...... ndependent of parkin activity.
@ast
MPTP and DSP-4 susceptibility ...... ndependent of parkin activity.
@en
type
label
MPTP and DSP-4 susceptibility ...... ndependent of parkin activity.
@ast
MPTP and DSP-4 susceptibility ...... ndependent of parkin activity.
@en
prefLabel
MPTP and DSP-4 susceptibility ...... ndependent of parkin activity.
@ast
MPTP and DSP-4 susceptibility ...... ndependent of parkin activity.
@en
P2093
P2860
P1476
MPTP and DSP-4 susceptibility ...... ndependent of parkin activity.
@en
P2093
Allen S Mandir
Bobby Thomas
Daniel B Trinkaus
Kah Leong Lim
M Flint Beal
Mohamed H Farah
Noel Y Calingasan
Rainer von Coelln
Valina L Dawson
P2860
P304
P356
10.1016/J.NBD.2006.12.021
P577
2007-01-25T00:00:00Z