ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair
about
Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forksPALB2: the hub of a network of tumor suppressors involved in DNA damage responsesPalb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancerCancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motifBRCA2 coordinates the activities of cell-cycle kinases to promote genome stabilityGenome-wide analysis reveals a role for BRCA1 and PALB2 in transcriptional co-activationA Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour DevelopmentConnecting chromatin modifying factors to DNA damage response.PALB2 and breast cancer: ready for clinical translation!Hypersensitivities for acetaldehyde and other agents among cancer cells null for clinically relevant Fanconi anemia genes.A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.The Role of PALB2 in the DNA Damage Response and Cancer Predisposition.Structural Basis for Multi-specificity of MRG Domains.MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress.PALB2 self-interaction controls homologous recombination.Characterization of a novel germline PALB2 duplication in a hereditary breast and ovarian cancer family.Perturbation of PALB2 function by the T413S mutation found in small cell lung cancer.
P2860
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P2860
ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@ast
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@en
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@en-gb
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@nl
type
label
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@ast
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@en
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@en-gb
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@nl
prefLabel
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@ast
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@en
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@en-gb
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@nl
P2093
P2860
P356
P1433
P1476
ChAM, a novel motif that media ...... ing and facilitates DNA repair
@en
P2093
Fumiko Esashi
Jean-Yves Bleuyard
Jean-Yves Masson
Rémi Buisson
P2860
P304
P356
10.1038/EMBOR.2011.243
P407
P577
2012-02-01T00:00:00Z