Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12
about
Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta.Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activityPotent inhibition of werner and bloom helicases by DNA minor groove binding drugsCharacterization of the human and mouse WRN 3'-->5' exonucleaseRegulation and localization of the Bloom syndrome protein in response to DNA damageThe Bloom's and Werner's syndrome proteins are DNA structure-specific helicasesRECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombinationThe Bloom's syndrome gene product is a 3'-5' DNA helicaseRecql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers.Identification of RecQL1 as a Holliday junction processing enzyme in human cell linesA subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRAAnalysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein AHuman RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biologyThe Bloom's syndrome gene product promotes branch migration of holliday junctionsHuman premature aging, DNA repair and RecQ helicasesCell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicaseCancer predisposition caused by elevated mitotic recombination in Bloom miceA novel protein interacts with the Werner's syndrome gene product physically and functionallyCovalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death.Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges.Distinct roles of RECQ1 in the maintenance of genomic stability.Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1+/- mice.Differential regulation of human RecQ family helicases in cell transformation and cell cycle.Sgs1 helicase activity is required for mitotic but apparently not for meiotic functions.Characterization of the DNA-unwinding activity of human RECQ1, a helicase specifically stimulated by human replication protein A.Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1.Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase.Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene.The level of RECQL1 expression is a prognostic factor for epithelial ovarian cancer.RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers.RECQL1 DNA repair helicase: a potential therapeutic target and a proliferative marker against ovarian cancer.Possible association of BLM in decreasing DNA double strand breaks during DNA replicationRecQ helicases: suppressors of tumorigenesis and premature aging.RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination.RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.Structure and function of RecQ DNA helicases.RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coliRECQ1 plays a distinct role in cellular response to oxidative DNA damage.
P2860
Q22253320-D9DFAA37-C6BD-46BC-972B-D7BDF3135DC8Q22254162-DA1FAC44-207B-4A58-B08A-57DDDE260BC8Q22254376-3D4535E9-8AB4-4484-81DF-67B8E5FE85F5Q22254412-5507DB7D-9827-4D4E-A660-2EBEE0B907D8Q24291133-6588730A-A637-46C1-A48A-8BC5D938FBCDQ24291390-F63D45A5-1C90-45FF-A0CA-C301EAA998DCQ24301788-C2BF02C3-7239-4A3B-B654-34D42729BA21Q24310523-7BB39BB4-47BD-44DE-8E9D-AC3B46F550B5Q24522689-B7E66D56-B185-4A8D-B0C5-EF95AC784372Q24536291-F3BACD54-F80D-4E0D-928B-3C568EE95AB6Q24545696-0252CB96-DAD1-4787-A207-24F5D0F1296EQ24563590-D617D195-CED2-4349-A8B0-194120110EADQ24620195-2FFF828F-0B73-42DA-A2ED-0EF8CE738D1BQ24674127-BB17D568-3EC0-462C-8F29-571E48124BFCQ24680996-F4EB5B7B-328D-4E6C-970A-DC15636CC9EDQ28138117-C16A85F9-AF72-45DE-875E-542761BDF2E4Q28139170-CF1CBBD5-8E5B-4B58-8F2B-A9708463238EQ28212274-26649DC2-67BF-4FA2-9452-573186400716Q28512334-3D4A477F-6A3C-4702-B127-99E1FA25FAC9Q31821369-59267C2F-7E54-4A41-BDEE-D606EFDCFB55Q33309941-A018EDCC-4C30-4968-95B2-51A2DD6B0512Q33684409-D32A4652-3077-464B-B3C9-FDE92AB473E9Q33786685-9BB0DB4D-E523-4641-B09E-7015330FF7FCQ33884558-40415027-BA1F-46DD-8D53-B1E243666FFEQ33921475-9ACC52D2-99A2-415A-9B09-BC7577F7E3B9Q33965180-414DDEDA-3CB8-4DC6-B3DC-F59ED14CD4FCQ34158015-16E3FF8A-5495-4541-8B8C-84E26EC95EABQ34419570-830615AC-4615-4AD3-A033-373C22E5DBF9Q34588305-A914D94D-1B91-4A13-B0F4-A3624A0F1BCEQ34606438-C9545FE3-EA3F-4656-9CB7-EF9C02268DE0Q34631089-E9BF20FD-352E-4E82-9F30-2986E5A9F951Q34885239-92258D33-B9AB-4680-B558-8D346CB70FA0Q34951783-4122639E-07C1-49D0-A406-C7896981B3BDQ35115298-B0E4C551-7375-4BE2-9AB5-BC4ADF221359Q35152970-7F92C983-68D3-43EF-B7D5-EA839C926388Q35196675-C24E27A6-3E77-4CB4-9879-AAE0098AE0B9Q35676137-851C79F3-D514-4C12-9813-DF25E3C982B9Q35817571-5857862A-EE7A-4F93-BBBB-DA33EB5313B5Q36106533-FE015557-0BF3-43CC-BF5F-A3F08BB0FEF5Q36167048-608533E0-4233-4073-93AC-428379987BD2
P2860
Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@ast
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@en
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@en-gb
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@nl
type
label
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@ast
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@en
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@en-gb
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@nl
prefLabel
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@ast
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@en
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@en-gb
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@nl
P2093
P2860
P356
P1476
Molecular cloning of cDNA enco ...... f the gene at chromosome 12p12
@en
P2093
H Miyazawa
J Yanagisawa
P2860
P304
P356
10.1093/NAR/22.22.4566
P407
P577
1994-11-11T00:00:00Z