Possible association of BLM in decreasing DNA double strand breaks during DNA replication
about
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replicationUV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalizationHomologous recombination: from model organisms to human disease.Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cellsRMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityManipulating mitotic recombination in the zebrafish embryo through RecQ helicasesOpposing roles for DNA structure-specific proteins Rad1, Msh2, Msh3, and Sgs1 in yeast gene targeting.The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repairFunctional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATMPotential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cellsEssential roles of BCCIP in mouse embryonic development and structural stability of chromosomesChromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogsNovel pro- and anti-recombination activities of the Bloom's syndrome helicase.Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres.RTEL1 contributes to DNA replication and repair and telomere maintenance.Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1.The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction.Mechanisms by which Bloom protein can disrupt recombination intermediates of Okazaki fragment maturation.The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cellsFunctional relationships of FANCC to homologous recombination, translesion synthesis, and BLMThe chicken as a model for large-scale analysis of vertebrate gene function.Manipulating the mammalian genome by homologous recombinationGenetic interactions between BLM and DNA ligase IV in human cells.Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase.BLM helicase stimulates the ATPase and chromatin-remodeling activities of RAD54.BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombinationWerner protein cooperates with the XRCC4-DNA ligase IV complex in end-processingRecQ helicases: suppressors of tumorigenesis and premature aging.The BLM dissolvasome in DNA replication and repair.Chromosomes and cancer cells.Mechanisms of leukemia translocationsIdentification and analysis of new proteins involved in the DNA damage response network of Fanconi anemia and Bloom syndrome.Genome instability and embryonic developmental defects in RMI1 deficient mice.Hitting the bull's eye: novel directed cancer therapy through helicase-targeted synthetic lethality.Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processingBloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinksRad54, the motor of homologous recombination.Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding.RecQ helicases; at the crossroad of genome replication, repair, and recombination.
P2860
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P2860
Possible association of BLM in decreasing DNA double strand breaks during DNA replication
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
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2000年論文
@zh-mo
2000年論文
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2000年论文
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Possible association of BLM in decreasing DNA double strand breaks during DNA replication
@ast
Possible association of BLM in decreasing DNA double strand breaks during DNA replication
@en
type
label
Possible association of BLM in decreasing DNA double strand breaks during DNA replication
@ast
Possible association of BLM in decreasing DNA double strand breaks during DNA replication
@en
prefLabel
Possible association of BLM in decreasing DNA double strand breaks during DNA replication
@ast
Possible association of BLM in decreasing DNA double strand breaks during DNA replication
@en
P2093
P2860
P356
P1433
P1476
Possible association of BLM in decreasing DNA double strand breaks during DNA replication
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/19.13.3428
P407
P577
2000-07-01T00:00:00Z