RecQ helicases: suppressors of tumorigenesis and premature aging.
about
BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrityRECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombinationStimulation of flap endonuclease-1 by the Bloom's syndrome proteinPhysical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicasesRegulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylationATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adductsBLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesGenome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulationThe RecQ DNA helicases in DNA repairHuman RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptidePhysical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein AUp-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaksHuman RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biologyModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingMore complexity to the Bloom's syndrome complexThe Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase deltaHuman RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication forkHuman premature aging, DNA repair and RecQ helicasesGlobal expression changes resulting from loss of telomeric DNA in fission yeastSrs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa.Poly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase I-dependent recombination stimulation by P53Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteinsEctopic Expression of Testis Germ Cell Proteins in Cancer and Its Potential Role in Genomic InstabilityCrystal structure of the HRDC domain of human Werner syndrome protein, WRNStructure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQStructure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome DissolvasomeDefining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasomeEnd-resection at DNA double-strand breaks in the three domains of lifeBinding and activation of DNA topoisomerase III by the Rmi1 subunit.Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disordersp14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicaseThe Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradationMutation of the murine Bloom's syndrome gene produces global genome destabilizationThe Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineageThe Bloom's syndrome helicase suppresses crossing over during homologous recombinationExpression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase.Novel pro- and anti-recombination activities of the Bloom's syndrome helicase.Redundancy of DNA helicases in p53-mediated apoptosis.
P2860
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P2860
RecQ helicases: suppressors of tumorigenesis and premature aging.
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
RecQ helicases: suppressors of tumorigenesis and premature aging.
@ast
RecQ helicases: suppressors of tumorigenesis and premature aging.
@en
type
label
RecQ helicases: suppressors of tumorigenesis and premature aging.
@ast
RecQ helicases: suppressors of tumorigenesis and premature aging.
@en
prefLabel
RecQ helicases: suppressors of tumorigenesis and premature aging.
@ast
RecQ helicases: suppressors of tumorigenesis and premature aging.
@en
P2860
P356
P1433
P1476
RecQ helicases: suppressors of tumorigenesis and premature aging
@en
P2093
Ian D Hickson
P2860
P304
P356
10.1042/BJ20030491
P407
P577
2003-09-01T00:00:00Z