Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1 - Test2 - elhamkhani - TriplyDB

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

http://www.wikidata.org/entity/Q24310249

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Huntingtin interacting proteins are genetic modifiers of neurodegeneration Evaluation of Dimebon in cellular model of Huntington's disease Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress Neuronal calcium sensor-1 enhancement of InsP3 receptor activity is inhibited by therapeutic levels of lithium Mitochondria, calcium and cell death: a deadly triad in neurodegeneration Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model Iron dysregulation in Huntington's disease Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability Huntingtin: alive and well and working in middle management Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype.Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3 Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1) has InsP(3)-independent gating and disrupts intracellular Ca(2+) homeostasis HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts.Huntingtin-associated protein 1: Eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1.Neuroprotective effects of calmodulin peptide 76-121aa: disruption of calmodulin binding to mutant huntingtin.Selective expression of Huntingtin-associated protein 1 in {beta}-cells of the rat pancreatic islets.Anesthetic-induced neurodegeneration mediated via inositol 1,4,5-trisphosphate receptors Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress.The enigma of store-operated ca-entry in neurons: answers from the Drosophila flight circuit.Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice.Tetrabenazine is neuroprotective in Huntington's disease mice.Susceptibility to Calcium Dysregulation during Brain Aging.Activity-dependent augmentation of spontaneous neurotransmission during endoplasmic reticulum stress Inositol trisphosphate receptor Ca2+ release channels in neurological diseases.Inositol trisphosphate receptor Ca2+ release channels.Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse.Calcium-dependent conformational changes in inositol trisphosphate receptors.Functional properties of the Drosophila melanogaster inositol 1,4,5-trisphosphate receptor mutants

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P2860

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

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2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Huntingtin and huntingtin-asso ...... ) triphosphate receptor type 1

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Anton Maximov

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Cheryl L Wellington

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Edmond Y W Chan

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Huiping Tu

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Ilya Bezprozvanny

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Tie-Shan Tang

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Zhengnan Wang

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P2860

A huntingtin-associated protein enriched in brain with implications for pathology

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain

A human HAP1 homologue. Cloning, expression, and interaction with huntingtin

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

Synaptic targeting of N-type calcium channels in hippocampal neurons

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Association of the type 1 inositol (1,4,5)-trisphosphate receptor with 4.1N protein in neurons

mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

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227-39

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3000384

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10.1016/S0896-6273(03)00366-0

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2

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Michael R. Hayden

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12873381

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ion channel binding

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3220623

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