Localization of LRRK2 to membranous and vesicular structures in mammalian brain - Test2 - elhamkhani - TriplyDB

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

http://www.wikidata.org/entity/Q24318643

about

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1 Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP Expression of leucine-rich repeat kinase 2 (LRRK2) inhibits the processing of uMtCK to induce cell death in a cell culture model system MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2 LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6 Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2)LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1 Identification of potential protein interactors of Lrrk2 Synaptic vesicle trafficking and Parkinson's disease Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export LRRK2 transport is regulated by its novel interacting partner Rab32 Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study ArfGAP1 is a GTPase activating protein for LRRK2: reciprocal regulation of ArfGAP1 by LRRK2 The role of oxidative stress in Parkinson's disease A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily GTP binding controls complex formation by the human ROCO protein MASL1 RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila Interplay of LRRK2 with chaperone-mediated autophagy Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons Mitochondria, calcium and cell death: a deadly triad in neurodegeneration Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells Intrabody and Parkinson's disease LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's Disease Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial Bioenergetics Genetically engineered mouse models of Parkinson's disease The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease The regulation and deregulation of Wnt signaling by PARK genes in health and disease Ten years and counting: moving leucine-rich repeat kinase 2 inhibitors to the clinic

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P2860

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

http://www.wikidata.org/entity/Q24318643

description

2006 nî lūn-bûn

@nan

2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

@zh-tw

2006年论文

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name

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@ast

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@en

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@en-gb

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@nl

type

label

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@ast

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@en

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@en-gb

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@nl

prefLabel

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@ast

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@en

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@en-gb

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

@nl

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Annals of Neurology

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Localization of LRRK2 to membranous and vesicular structures in mammalian brain

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P2093

Darren J Moore

http://www.w3.org/2001/XMLSchema#string

Joseph M Savitt

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Kaisa Kurkinen

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Piers C Emson

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Reidun Torp

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Richard L M Faull

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Saskia Biskup

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Seong-Woon Yu

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Shaida A Andrabi

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Shinji Higashi

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557-69

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scholarly article

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1364131

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10.1002/ANA.21019

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5

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60

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Valina L. Dawson

Henry J. Waldvogel

Ole Petter Ottersen

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2006-11-01T00:00:00Z

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6678311

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17120249

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P921

Leucine-rich repeat kinase 2

Leucine rich repeat kinase 2