Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
about
Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queriesIntegrative annotation of variants from 1092 humans: application to cancer genomicsp31comet blocks Mad2 activation through structural mimicryFAT10 plays a role in the regulation of chromosomal stabilityDeterminants of conformational dimerization of Mad2 and its inhibition by p31cometProbing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpointAPC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachmentConformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpointSpindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochoreStructural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template modelMad2 overexpression promotes aneuploidy and tumorigenesis in miceThe multifaceted roles of the HORMA domain in cellular signalingThe current view for the silencing of the spindle assembly checkpointStructure of the mitotic checkpoint complexThe APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.In-silico modeling of the mitotic spindle assembly checkpointConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint.A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.The influence of catalysis on mad2 activation dynamics.Evaluating putative mechanisms of the mitotic spindle checkpointATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpointRemoval of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cellsThe spindle checkpoint, aneuploidy, and cancer.Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet).Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing proteinThe dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregationPhosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition.p31comet Promotes disassembly of the mitotic checkpoint complex in an ATP-dependent processThe biochemistry of mitosisTopoisomerase IIα in chromosome instability and personalized cancer therapy.p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachmentMutual regulation between the spindle checkpoint and APC/C.p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switchingRole of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complexMode of interaction of TRIP13 AAA-ATPase with the Mad2-binding protein p31comet and with mitotic checkpoint complexes.RanGTP aids anaphase entry through Ubr5-mediated protein turnover.p31comet-Induced Cell Death Is Mediated by Binding and Inactivation of Mad2.An E2 enzyme Ubc11 is required for ubiquitination of Slp1/Cdc20 and spindle checkpoint silencing in fission yeast
P2860
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P2860
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Identification of a MAD2-binding protein, CMT2, and its role in mitosis
@nl
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@ast
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@en
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@en-gb
type
label
Identification of a MAD2-binding protein, CMT2, and its role in mitosis
@nl
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@ast
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@en
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@en-gb
prefLabel
Identification of a MAD2-binding protein, CMT2, and its role in mitosis
@nl
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@ast
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@en
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@en-gb
P2093
P2860
P356
P1433
P1476
Identification of a MAD2-binding protein, CMT2, and its role in mitosis.
@en
P2093
Jasminder Weinstein
Sang Hoon Kim
Tomohiro Matsumoto
Toshiyuki Habu
P2860
P304
P356
10.1093/EMBOJ/CDF659
P407
P577
2002-12-01T00:00:00Z