Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells - Test2 - elhamkhani - TriplyDB

Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

http://www.wikidata.org/entity/Q33816797

about

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint Moonlighting functions of the NRZ (mammalian Dsl1) complex The current view for the silencing of the spindle assembly checkpoint KNL1: bringing order to the kinetochore Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit Kinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema A Centromere-Signaling Network Underlies the Coordination among Mitotic Events Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.The Ndc80 complex: integrating the kinetochore's many movements.Spindle poisons and cell fate: a tale of two pathways.Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation.F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Mechanism and regulation of cytoplasmic dynein Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase.Spatial-temporal model for silencing of the mitotic spindle assembly checkpoint Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.Spindle checkpoint silencing: ensuring rapid and concerted anaphase onset Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest Polo-like kinase1 is required for recruitment of dynein to kinetochores during mitosis A maternal effect rough deal mutation suggests that multiple pathways regulate Drosophila RZZ kinetochore recruitment.Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces.Mutual regulation between the spindle checkpoint and APC/C.Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors.Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore.Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction RanGTP aids anaphase entry through Ubr5-mediated protein turnover.Dynamic ASXL1 Exon Skipping and Alternative Circular Splicing in Single Human Cells.Systematic dissection of dynein regulators in mitosis How the SAC gets the axe: Integrating kinetochore microtubule attachments with spindle assembly checkpoint signaling.Making an effective switch at the kinetochore by phosphorylation and dephosphorylation.

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Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

http://www.wikidata.org/entity/Q33816797

description

2010 nî lūn-bûn

@nan

2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

@wuu

name

Removal of Spindly from microt ...... point silencing in human cells

@ast

Removal of Spindly from microt ...... point silencing in human cells

@en

type

label

Removal of Spindly from microt ...... point silencing in human cells

@ast

Removal of Spindly from microt ...... point silencing in human cells

@en

prefLabel

Removal of Spindly from microt ...... point silencing in human cells

@ast

Removal of Spindly from microt ...... point silencing in human cells

@en

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Genes & Development

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Removal of Spindly from microt ...... point silencing in human cells

@en

P2093

Andrew J Holland

http://www.w3.org/2001/XMLSchema#string

Arshad Desai

http://www.w3.org/2001/XMLSchema#string

Dileep Varma

http://www.w3.org/2001/XMLSchema#string

Edward D Salmon

http://www.w3.org/2001/XMLSchema#string

Filiz Civril

http://www.w3.org/2001/XMLSchema#string

Xiaohu Wan

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

p31comet blocks Mad2 activation through structural mimicry

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

Conservation of the centromere/kinetochore protein ZW10

Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.

The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes

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957-971

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scholarly article

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10.1101/GAD.1886810

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9

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24

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Don W Cleveland

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2010-05-01T00:00:00Z

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44570354

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20439434

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P932

2861194

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