Multiple roles of ATM in monitoring and maintaining DNA integrity - Test2 - elhamkhani - TriplyDB

Multiple roles of ATM in monitoring and maintaining DNA integrity

Multiple roles of ATM in monitoring and maintaining DNA integrity

http://www.wikidata.org/entity/Q24594847

about

Cancer genome landscapes ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair Shelterin complex and associated factors at human telomeres CHK1 inhibitors in combination chemotherapy: thinking beyond the cell cycle Mitochondrial dysfunction in ataxia-telangiectasia Impact of CDT Toxin on Human Diseases When heat casts a spell on the DNA damage checkpoints Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling Ataxia telangiectasia: a review Role of RUNX2 in Breast Carcinogenesis Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans DNA damage response genes and the development of cancer metastasis Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint The intersection between DNA damage response and cell death pathways Mechanisms for Structural Variation in the Human Genome Differential expression of stress and immune response pathway transcripts and miRNAs in normal human endothelial cells subjected to fractionated or single-dose radiation.Interplay of DNA damage and cell cycle signaling at the level of human replication protein A Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition.O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation.ATM signalling and cancer.cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle MicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer Human T-lymphotropic virus type 1 p30 interacts with REGgamma and modulates ATM (ataxia telangiectasia mutated) to promote cell survival.ATM gene mutations in sporadic breast cancer patients from Brazil.Ten new ATM alterations in Polish patients with ataxia-telangiectasia.Choosing the right path: does DNA-PK help make the decision?DNA double strand breaks as predictor of efficacy of the alpha-particle emitter Ac-225 and the electron emitter Lu-177 for somatostatin receptor targeted radiotherapy.Can the DNA damage response be harnessed to modulate atherosclerotic plaque phenotype?Relationships of FOXE1 and ATM genetic polymorphisms with papillary thyroid carcinoma risk: a meta-analysis.Mutations in PNKP cause recessive ataxia with oculomotor apraxia type 4.Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.SCF ubiquitin ligases in the maintenance of genome stability.ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila.All stressed out without ATM kinase Gold-containing indoles as anticancer agents that potentiate the cytotoxic effects of ionizing radiation.

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P2860

Multiple roles of ATM in monitoring and maintaining DNA integrity

http://www.wikidata.org/entity/Q24594847

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

@wuu

name

Multiple roles of ATM in monitoring and maintaining DNA integrity

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Multiple roles of ATM in monitoring and maintaining DNA integrity

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Multiple roles of ATM in monitoring and maintaining DNA integrity

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type

label

Multiple roles of ATM in monitoring and maintaining DNA integrity

@ast

Multiple roles of ATM in monitoring and maintaining DNA integrity

@en

Multiple roles of ATM in monitoring and maintaining DNA integrity

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prefLabel

Multiple roles of ATM in monitoring and maintaining DNA integrity

@ast

Multiple roles of ATM in monitoring and maintaining DNA integrity

@en

Multiple roles of ATM in monitoring and maintaining DNA integrity

@nl

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J.FEBSLET.2010.05.031

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P1476

Multiple roles of ATM in monitoring and maintaining DNA integrity

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Frederick A Derheimer

http://www.w3.org/2001/XMLSchema#string

Michael B Kastan

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P2860

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

Common mechanisms of PIKK regulation

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3675-81

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scholarly article

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4533407

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10.1016/J.FEBSLET.2010.05.031

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17

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44802641

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20580718

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structural biology

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2950315

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