Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
about
Kinetochore-microtubule interactions: steps towards bi-orientationCell division: control of the chromosomal passenger complex in time and spaceReconstituting the kinetochore–microtubule interface: what, why, and howGSK3 regulates mitotic chromosomal alignment through CRMP4Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore.Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signallingChemical genetic inhibition of Mps1 in stable human cell lines reveals novel aspects of Mps1 function in mitosisQuantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly.Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex.High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells.Mps1 promotes rapid centromere accumulation of Aurora B.Correcting aberrant kinetochore microtubule attachments: an Aurora B-centric view.The MPS1 family of protein kinases.Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacyN-terminal regions of Mps1 kinase determine functional bifurcation.Changing partners: moving from non-homologous to homologous centromere pairing in meiosis.Finding the middle ground: how kinetochores power chromosome congression.Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversineMps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint.Live-cell analysis of kinetochore-microtubule interaction in budding yeast.Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progressionSensing centromere tension: Aurora B and the regulation of kinetochore function.Bub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast.Measuring kinetochore-microtubule interaction in vitro.A maternal effect rough deal mutation suggests that multiple pathways regulate Drosophila RZZ kinetochore recruitment.Correction of microtubule-kinetochore attachment errors: mechanisms and role in tumor suppression.Mitotic spindle form and functionDynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachmentSpindle checkpoint-independent inhibition of mitotic chromosome segregation by Drosophila Mps1.Kinetochore-microtubule interactions: the means to the endMps1 and Ipl1/Aurora B act sequentially to correctly orient chromosomes on the meiotic spindle of budding yeast.Making an effective switch at the kinetochore by phosphorylation and dephosphorylation.The composition, functions, and regulation of the budding yeast kinetochoreEffects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs.Mechanisms of Chromosome Congression during Mitosis.Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer.A chemical tool box defines mitotic and interphase roles for Mps1 kinase.Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.
P2860
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P2860
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@ast
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@en
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism.
@nl
type
label
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@ast
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@en
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism.
@nl
altLabel
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@en
prefLabel
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@ast
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@en
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism.
@nl
P2860
P1433
P1476
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
@en
P2093
Jean-François Maure
P2860
P304
P356
10.1016/J.CUB.2007.11.032
P407
P577
2007-11-29T00:00:00Z