Mps1 promotes rapid centromere accumulation of Aurora B. - Test2 - elhamkhani - TriplyDB

Mps1 promotes rapid centromere accumulation of Aurora B.

Mps1 promotes rapid centromere accumulation of Aurora B.

http://www.wikidata.org/entity/Q30524672

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A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling Cell division: control of the chromosomal passenger complex in time and space Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint A Centromere-Signaling Network Underlies the Coordination among Mitotic Events Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B.Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing.Spatial regulation of the spindle assembly checkpoint and anaphase-promoting complex in Aspergillus nidulans Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests Cyclin B3 controls anaphase onset independent of spindle assembly checkpoint in meiotic oocytes.Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524.The composition, functions, and regulation of the budding yeast kinetochore Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase.Signalling dynamics in the spindle checkpoint response.Shugoshins: tension-sensitive pericentromeric adaptors safeguarding chromosome segregation Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression.Regulation of mitotic progression by the spindle assembly checkpoint Shugoshin-1 balances Aurora B kinase activity via PP2A to promote chromosome bi-orientation.TC Mps1 12, a novel Mps1 inhibitor, suppresses the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability.Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores.The Ska complex promotes Aurora B activity to ensure chromosome biorientation.Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I.Budding yeast CENP-ACse4 interacts with the N-terminus of Sgo1 and regulates its association with centromeric chromatin.Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores.The Ins and Outs of Aurora B Inner Centromere Localization.Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics.GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms.Multiple Duties for Spindle Assembly Checkpoint Kinases in Meiosis.A Kinase-Phosphatase Network that Regulates Kinetochore-Microtubule Attachments and the SAC.Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis.Kinase and Phosphatase Cross-Talk at the Kinetochore.

P2860

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P2860

Mps1 promotes rapid centromere accumulation of Aurora B.

http://www.wikidata.org/entity/Q30524672

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Mps1 promotes rapid centromere accumulation of Aurora B.

@ast

Mps1 promotes rapid centromere accumulation of Aurora B.

@en

type

label

Mps1 promotes rapid centromere accumulation of Aurora B.

@ast

Mps1 promotes rapid centromere accumulation of Aurora B.

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prefLabel

Mps1 promotes rapid centromere accumulation of Aurora B.

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Mps1 promotes rapid centromere accumulation of Aurora B.

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P1433

P1476

Mps1 promotes rapid centromere accumulation of Aurora B.

@en

P2093

Claudia Wurzenberger

http://www.w3.org/2001/XMLSchema#string

Daniel W Gerlich

http://www.w3.org/2001/XMLSchema#string

Geert J P L Kops

http://www.w3.org/2001/XMLSchema#string

Maike S van der Waal

http://www.w3.org/2001/XMLSchema#string

Martijn J M Vromans

http://www.w3.org/2001/XMLSchema#string

Mathijs Vleugel

http://www.w3.org/2001/XMLSchema#string

Susanne M A Lens

http://www.w3.org/2001/XMLSchema#string

P2860

Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction.

Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment

Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function

Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Chemical genetic inhibition of Mps1 in stable human cell lines reveals novel aspects of Mps1 function in mitosis

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

P304

847-854

http://www.w3.org/2001/XMLSchema#string

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scholarly article

P356

10.1038/EMBOR.2012.93

http://www.w3.org/2001/XMLSchema#string

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P50

René H. Medema

Mathijs Vleugel

P577

2012-06-26T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

228066102

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P698

22732840

http://www.w3.org/2001/XMLSchema#string

P932

3432816

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