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A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processesFlotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sortingCanonical and Non-canonical Reelin SignalingCurrent Research Therapeutic Strategies for Alzheimer's Disease TreatmentTau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic ParaplegiaForty Years of Clathrin-coated VesiclesMisframed ubiquitin and impaired protein quality control: an early event in Alzheimer's diseaseMetabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and TreatmentNeural Plasticity in Multiple Sclerosis: The Functional and Molecular BackgroundDual roles for autophagy: degradation and secretion of Alzheimer's disease Aβ peptideTrafficking regulation of proteins in Alzheimer's diseaseApolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer diseaseInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseAlzheimer's pathogenesis and its link to the mitochondrionAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseGolgi defects enhance APP amyloidogenic processing in Alzheimer's diseaseRoles of vascular and metabolic components in cognitive dysfunction of Alzheimer disease: short- and long-term modification by non-genetic risk factorsStructural biology of presenilin 1 complexesAlzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasisAmyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal NeuronsAPP intracellular domain-WAVE1 pathway reduces amyloid-β production.AAV2/1 CD74 Gene Transfer Reduces β-amyloidosis and Improves Learning and Memory in a Mouse Model of Alzheimer's Disease.Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation.Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β 2 -MicroglobulinGenetic variants associated with neurodegenerative Alzheimer disease in natural modelsCurrent and future implications of basic and translational research on amyloid-β peptide production and removal pathwaysThe preclinical phase of the pathological process underlying sporadic Alzheimer's diseaseProtein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitusAmyloid-precursor-protein-lowering small molecules for disease modifying therapy of Alzheimer's diseaseAn Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase ActivityEffects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model.DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease.Differential release of β-amyloid from dendrite- versus axon-targeted APP.Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes.Alzheimer's disease: pathophysiology and applications of magnetic nanoparticles as MRI theranostic agents.Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development.Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production.Genetically modified pig models for neurodegenerative disorders.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Trafficking and proteolytic processing of APP
@ast
Trafficking and proteolytic processing of APP
@en
Trafficking and proteolytic processing of APP
@nl
type
label
Trafficking and proteolytic processing of APP
@ast
Trafficking and proteolytic processing of APP
@en
Trafficking and proteolytic processing of APP
@nl
prefLabel
Trafficking and proteolytic processing of APP
@ast
Trafficking and proteolytic processing of APP
@en
Trafficking and proteolytic processing of APP
@nl
P2093
P2860
P3181
P1476
Trafficking and proteolytic processing of APP
@en
P2093
Christoph Kaether
Gopal Thinakaran
Sangram Sisodia
P2860
P304
P3181
P356
10.1101/CSHPERSPECT.A006270
P407
P577
2012-05-01T00:00:00Z