Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein - Test2 - elhamkhani - TriplyDB

Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein

Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein

http://www.wikidata.org/entity/Q28298111

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The generation and function of soluble apoE receptors in the CNS The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1 Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding.Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families The solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated protein Long noncoding RNAs and Alzheimer's disease Trafficking regulation of proteins in Alzheimer's disease APP processing in Alzheimer's disease Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding Sortilin is upregulated during osteoblastic differentiation of mesenchymal stem cells and promotes extracellular matrix mineralization The carboxy-terminal domain of the receptor-associated protein binds to the Vps10p domain of sortilin Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography BCR/ABL-mediated downregulation of genes implicated in cell adhesion and motility leads to impaired migration toward CCR7 ligands CCL19 and CCL21 in primary BCR/ABL-positive cells Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related protein The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy Functional organization of the sortilin Vps10p domain.SorCS3 does not require propeptide cleavage to bind nerve growth factor.Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.The discovery of indole full agonists of the neurotensin receptor 1 (NTSR1).Impact of genetic variation in SORCS1 on memory retention.Multi-compartmental modeling of SORLA's influence on amyloidogenic processing in Alzheimer's disease A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes.The role of apolipoprotein E in Alzheimer's disease.The genetic variation of SORCS1 is associated with late-onset Alzheimer's disease in Chinese Han population.SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk.Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression.Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.

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Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein

http://www.wikidata.org/entity/Q28298111

description

1996 nî lūn-bûn

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1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1996年の論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年论文

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P2860

Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain

Apolipoprotein E and Alzheimer disease

Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor

The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene.

New perspectives in cell adhesion: RGD and integrins

Patterns of amino acids near signal-sequence cleavage sites

Molecular cloning of NILE glycoprotein and evidence for its continued expression in mature rat CNS.

A G protein-coupled receptor with low density lipoprotein-binding motifs suggests a role for lipoproteins in G-linked signal transduction

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49

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