Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation
about
ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formationNIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP, a PEST-containing nuclear proteinThe USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expressionUHRF1 plays a role in maintaining DNA methylation in mammalian cellsNIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressorCritical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth.Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomicsNp95 is a histone-binding protein endowed with ubiquitin ligase activityICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cellsModifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseNIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscapeStructural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) ProteinCooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathwaysUHRF1 is a genome caretaker that facilitates the DNA damage response to gamma-irradiationVIM1, a methylcytosine-binding protein required for centromeric heterochromatinization.Liver growth in the embryo and during liver regeneration in zebrafish requires the cell cycle regulator, uhrf1UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis.Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencingHydroxymethylation of DNA: an epigenetic marker.S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenanceNp95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entryUHRF1 overexpression is involved in cell proliferation and biochemical recurrence in prostate cancer after radical prostatectomyNegative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer.Negative regulation of the acetyltransferase TIP60-p53 interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1).Intranuclear degradation of polyglutamine aggregates by the ubiquitin-proteasome system.Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells.Elevated UHRF1 expression contributes to poor prognosis by promoting cell proliferation and metastasis in hepatocellular carcinoma.Adenovirus-mediated expression of UHRF1 reduces the radiosensitivity of cervical cancer HeLa cells to gamma-irradiationThe Roles of the Methyl-CpG Binding Proteins in Cancer.Regulation of maintenance DNA methylation via histone ubiquitylation.DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.UHRF1 confers radioresistance to human breast cancer cells.Targeted disruption of Np95 gene renders murine embryonic stem cells hypersensitive to DNA damaging agents and DNA replication blocks.UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoterDepletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts.UHRF1 is associated with tumor recurrence in non-muscle-invasive bladder cancer.Uhrf2 deletion impairs the formation of hippocampus-dependent memory by changing the structure of the dentate gyrus.NtSET1, a member of a newly identified subgroup of plant SET-domain-containing proteins, is chromatin-associated and its ectopic overexpression inhibits tobacco plant growth.UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.
P2860
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P2860
Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation
description
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Dezember 1998 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1998/12/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/12/01)
@nl
наукова стаття, опублікована в грудні 1998
@uk
مقالة علمية (نشرت في ديسمبر 1998)
@ar
name
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@ast
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@en
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@nl
type
label
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@ast
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@en
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@nl
prefLabel
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@ast
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@en
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@nl
P2093
P3181
P356
P1433
P1476
Cloning and mapping of Np95 ge ...... ciated with cell proliferation
@en
P2093
A. Fujimori
K. Tatsumi
R. Fukumura
Y. Hashimoto
Y. Matsuda
Y. Takemoto
P2888
P304
P3181
P356
10.1007/S003359900920
P577
1998-12-01T00:00:00Z