Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR1
about
Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in miceLinks between mutant p53 and genomic instabilityTranscriptional control of mitosis: deregulation and cancerTAp73 regulates the spindle assembly checkpoint by modulating BubR1 activityGenomic and epigenetic instability in colorectal cancer pathogenesis.The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B.The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2p53: guardian of ploidyNitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of cysteines 93 and 310Mitotic genes are transcriptionally upregulated in the fibroblast irradiated with very low doses of UV-CP53, cyclin-dependent kinase and abnormal amplification of centrosomes.Molecular pathways involved in colorectal cancer: implications for disease behavior and preventionMdmX regulates transformation and chromosomal stability in p53-deficient cells.TP53 mutations, expression and interaction networks in human cancersThe cancer biology of whole-chromosome instability.Genomic alterations as mediators of miRNA dysregulation in ovarian cancer.Centrosome amplification: a suspect in breast cancer and racial disparities.Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines.Contribution of BubR1 to oxidative stress-induced aneuploidy in p53-deficient cells.Centrosome aberrations associated with cellular senescence and p53 localization at supernumerary centrosomes.RAF associates with phosphorylated nuclear BubR1 during endoreduplication induced by JAK inhibition.CENPA overexpression promotes genome instability in pRb-depleted human cells.BubR1 localizes to centrosomes and suppresses centrosome amplification via regulating Plk1 activity in interphase cells.ECRG2 disruption leads to centrosome amplification and spindle checkpoint defects contributing chromosome instability.EDD, a ubiquitin-protein ligase of the N-end rule pathway, associates with spindle assembly checkpoint components and regulates the mitotic response to nocodazole.BUBR1 overexpression predicts disease-specific survival after nephroureterectomy in patients with upper tract urothelial carcinoma.Spindle assembly checkpoint protein Cdc20 transcriptionally activates expression of ubiquitin carrier protein UbcH10Mitotic Kinases and p53 Signaling.Hexavalent chromium induces energy metabolism disturbance and p53-dependent cell cycle arrest via reactive oxygen species in L-02 hepatocytes.The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.The resurrection of the PIDDosome - emerging roles in the DNA-damage response and centrosome surveillance.Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.USP49 participates in the DNA damage response by forming a positive feedback loop with p53.
P2860
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P2860
Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR1
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Transcriptional control of Bub ...... trosome amplification by BubR1
@ast
Transcriptional control of Bub ...... trosome amplification by BubR1
@en
type
label
Transcriptional control of Bub ...... trosome amplification by BubR1
@ast
Transcriptional control of Bub ...... trosome amplification by BubR1
@en
prefLabel
Transcriptional control of Bub ...... trosome amplification by BubR1
@ast
Transcriptional control of Bub ...... trosome amplification by BubR1
@en
P2093
P2860
P1476
Transcriptional control of Bub ...... trosome amplification by BubR1
@en
P2093
Hajime Tsujimoto
Hisashi Inokuma
Kenji Fukasawa
Masaru Okuda
Rakesh Goorha
Tatsuo Oikawa
Zhiyong Ma
P2860
P304
P356
10.1128/MCB.25.10.4046-4061.2005
P407
P577
2005-05-01T00:00:00Z