Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling - Test2 - elhamkhani - TriplyDB

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

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Insights into APC/C: from cellular function to diseases and therapeutics The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells.The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint.The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation.A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.Bub1/BubR1: swiss army knives at kinetochores.The DNA replication protein Cdc6 inhibits the microtubule-organizing activity of the centrosome.Oral lichen planus and malignant transformation: The role of p16, Ki-67, Bub-3 and SOX4 in assessing precancerous potential.Structural insights into the functional diversity of the CDK-cyclin family

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Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

http://www.wikidata.org/entity/Q34407585

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2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@ast

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@en

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

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label

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@ast

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@en

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@nl

prefLabel

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@ast

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@en

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@nl

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PNAS.1416277111

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

@en

P2093

Joo Seok Han

http://www.w3.org/2001/XMLSchema#string

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The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression

A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting

BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment

Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

Structural analysis of Bub3 interactions in the mitotic spindle checkpoint

Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.

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E4185-93

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scholarly article

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10.1073/PNAS.1416277111

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40

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111

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Daniele Fachinetti

Don W Cleveland

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2014-09-22T00:00:00Z

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265907152

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25246557

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4210015

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