Multiple functions of p27(Kip1) and its alterations in tumor cells: a review. - Test2 - elhamkhani - TriplyDB

Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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Highlight: BRCA1 and BRCA2 proteins in breast cancer Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1 Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat A single-nucleotide polymorphism in the human p27kip1 gene (-838C>A) affects basal promoter activity and the risk of myocardial infarction Micro(RNA)managing endoplasmic reticulum stress Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1 Autocrine human growth hormone inhibits placental transforming growth factor-beta gene transcription to prevent apoptosis and allow cell cycle progression of human mammary carcinoma cells Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogene The gap junction-independent tumor-suppressing effect of connexin 43 Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors Proliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines Bayesian hierarchical spatially correlated functional data analysis with application to colon carcinogenesis.Fast methods for spatially correlated multilevel functional data Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.Aberrant cell cycle regulation in cervical carcinoma.p27(Kip1) deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process.The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.p27 suppresses arsenite-induced Hsp27/Hsp70 expression through inhibiting JNK2/c-Jun- and HSF-1-dependent pathways.Ubiquitin-mediated proteolysis of vertebrate G1- and S-phase regulators.Long-term quiescent fibroblast cells transit into senescence Endothelin-1 inhibits apoptosis in prostate cancer Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region p27Kip1 inhibition of GRB2-SOS formation can regulate Ras activation.CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.SIRT1 inactivation evokes antitumor activities in NSCLC through the tumor suppressor p27.Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization Far upstream element binding protein 1 activates translation of p27Kip1 mRNA through its internal ribosomal entry site The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis.Epithelial stem cells in human prostate growth and disease.Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon.A crosstalk imbalance between p27(Kip1) and its interacting molecules enhances breast carcinogenesis Expression of p27, cyclin E and cyclin A in hepatocellular carcinoma and its clinical significance.Histone Deacetylase Inhibitors Increase p27(Kip1) by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells.Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21 Molecular mechanism underlying the functional loss of cyclindependent kinase inhibitors p16 and p27 in hepatocellular carcinoma

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P2860

Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

http://www.wikidata.org/entity/Q33853215

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2000 nî lūn-bûn

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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2000 թվականի ապրիլին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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type

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Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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Multiple functions of p27(Kip1) and its alterations in tumor cells: a review.

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P2860

Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

The retinoblastoma protein and cell cycle control

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