Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.
about
In vitro nuclear interactome of the HIV-1 Tat proteinCdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin bindingIdentification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosisHuman cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication.Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycleSpatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis.Subsets of human origin recognition complex (ORC) subunits are expressed in non-proliferating cells and associate with non-ORC proteinsThe SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradationCyclin-dependent kinases prevent DNA re-replication through multiple mechanismsNuclear organization of DNA replication initiation proteins in mammalian cellsCDC6: from DNA replication to cell cycle checkpoints and oncogenesisCellular checkpoint mechanisms monitoring proper initiation of DNA replicationCdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A.The APC/C inhibitor, Emi1, is essential for prevention of rereplicationIn vivo dynamics of EBNA1-oriP interaction during latent and lytic replication of Epstein-Barr virus.Expression of centromere protein F (CENP-F) associated with higher FDG uptake on PET/CT, detected by cDNA microarray, predicts high-risk patients with primary breast cancer.Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein-Barr virus replication compartments.Architecture of replication compartments formed during Epstein-Barr virus lytic replication.Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.Association of human origin recognition complex 1 with chromatin DNA and nuclease-resistant nuclear structures.Multiple mechanisms regulate subcellular localization of human CDC6.The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle.Control of DNA replication licensing in a cell cycle.The functional role of Cdc6 in S-G2/M in mammalian cells.Mutation of cyclin/cdk phosphorylation sites in HsCdc6 disrupts a late step in initiation of DNA replication in human cellsPhosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication.Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cyclep16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer.Eukaryotic MCM proteins: beyond replication initiation.SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication.DNA replication licensing and cell cycle kinetics of oligodendroglial tumours.Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells.DnaA, ORC, and Cdc6: similarity beyond the domains of life and diversity.Control over DNA replication in time and space.Relationship between DNA replication and the nuclear matrix.Imaging Cell Cycle Phases and Transitions of Living Cells from Yeast to Woman.Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional controDynamic changes in nuclear localization of a DNA-binding protein tyrosine phosphatase TCPTP in response to DNA damage and replication arrest.
P2860
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P2860
Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cell cycle regulation of human ...... mediated hyperphosphorylation.
@ast
Cell cycle regulation of human ...... mediated hyperphosphorylation.
@en
type
label
Cell cycle regulation of human ...... mediated hyperphosphorylation.
@ast
Cell cycle regulation of human ...... mediated hyperphosphorylation.
@en
prefLabel
Cell cycle regulation of human ...... mediated hyperphosphorylation.
@ast
Cell cycle regulation of human ...... mediated hyperphosphorylation.
@en
P2093
P2860
P356
P1476
Cell cycle regulation of human ...... -mediated hyperphosphorylation
@en
P2093
P2860
P304
25927-25932
P356
10.1074/JBC.274.36.25927
P407
P577
1999-09-01T00:00:00Z