Mitotic chromosomal instability and cancer: mouse modelling of the human disease. - Test2 - elhamkhani - TriplyDB

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

http://www.wikidata.org/entity/Q33926467

about

Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as an in vitro cell model for Erbb2 The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components Deficient spindle assembly checkpoint in multiple myeloma MTBP plays a crucial role in mitotic progression and chromosome segregation Chromosomal instability and cancer: a complex relationship with therapeutic potential Aneuploidy in stem cells Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis Reconstituting the kinetochore–microtubule interface: what, why, and how Prognostic value of Aurora kinase A (AURKA) expression among solid tumor patients: a systematic review and meta-analysis Aneuploidy-induced cellular stresses limit autophagic degradation.Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation Predisposition to cancer caused by genetic and functional defects of mammalian Atad5 Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.Structure of the human cohesin inhibitor Wapl PSMB8 and PBK as potential gastric cancer subtype-specific biomarkers associated with prognosis.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint Identification of aneuploidy-tolerating mutations Impact of genomic damage and ageing on stem cell function Reprogramming to pluripotency can conceal somatic cell chromosomal instability A screen for selective killing of cells with chromosomal instability induced by a spindle checkpoint defect USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis The accuracy of survival time prediction for patients with glioma is improved by measuring mitotic spindle checkpoint gene expression The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival.Unraveling the biomolecular snapshots of mitosis in healthy and cancer cells using plasmonically-enhanced Raman spectroscopy.Meta-analysis of Aurora Kinase A (AURKA) Expression Data Reveals a Significant Correlation Between Increased AURKA Expression and Distant Metastases in Human ER-positive Breast Cancers.SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.The role of chromosome missegregation in cancer development: a theoretical approach using agent-based modelling Expression of the microtubule-associated protein MAP9/ASAP and its partners AURKA and PLK1 in colorectal and breast cancers.MYC and the control of DNA replication.Tumor suppressor roles of CENP-E and Nsl1 in Drosophila epithelial tissues.Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive Causes and consequences of centrosome abnormalities in cancer.Rolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies.The origins of cancer robustness and evolvability.Prognostic significance and therapeutic implications of centromere protein F expression in human nasopharyngeal carcinoma

P2860

Q21134904-FF2496C0-B089-466F-93B3-0704A61E8173 Q21144957-93C45081-43C7-4658-9E39-D00A0531291D Q21560908-08AB15F4-8FC1-43BD-A4C3-5E3974AAA206 Q24338557-4D77831E-3FDE-4152-A79D-94AFB8D8C5F1 Q24608609-70C31862-1690-4567-B8D5-1D54EB310B32 Q26746154-D0B0508F-07D5-431C-8294-0C3EBABE02AB Q26998944-A39B2E94-D74C-4CB7-9B15-54E461FC3717 Q27007105-6C103104-1A51-447C-81FA-6BFB03243315 Q27024067-D03F193C-98AD-42FB-857F-860FDFE3C0CC Q27322688-19150FD0-DF17-406B-A180-AAECC605F01A Q27329025-C14B5300-1C13-4619-B99B-3A01CCD1413A Q27336379-326F03D1-28EB-4E0F-8383-CA1192258740 Q27346737-FD1F5769-B1B1-4DFF-9A5B-0E1BFF502B76 Q27678658-2EBBDA28-E356-4CB5-9F33-B30C38C82B68 Q27853348-AC4C3D0C-6808-4F32-BF9C-86B6CE365719 Q27940191-F630574B-D966-4E3E-83BC-430E2A06B42E Q28075699-CCFA7C04-7850-43B5-B711-1D5F83FD2B73 Q28293578-9121CC68-109A-46FC-86D7-A59F1AD42917 Q28308125-6438A4D7-CF98-4D5A-BB07-B57A24873B6B Q28483105-83ED1956-89D2-436F-836F-43A350AC56C2 Q28484384-A8A089A2-BC53-4EBD-90B0-3C7147763C9E Q28508251-F98CC3B8-A818-4695-A208-A34A04C2E7F0 Q28743982-64E050CC-7165-4954-B805-27C5A92FDECC Q28771737-2031ECF7-9B8A-44CE-A35B-DACCBE30BD22 Q30540402-D4F7A7CE-D715-4C6B-B491-937C0FC96320 Q30587039-AD0A7C8E-2B76-4261-BF21-BF3852E34D22 Q30598954-9BD77FD7-AFFF-4405-8D30-F2C09285D0C9 Q30800052-3AB0E354-3A3F-4F94-8849-A7CCF99C9D2C Q30822375-82A38DA5-B775-4E6F-8B88-16566864564E Q30854449-7F44D331-3863-47DC-BAC0-D0DBC9E8F77C Q31132456-670C084D-8ABE-4AF0-90A4-5E771067AA50 Q33616077-A91425F0-AAF3-4D68-B028-34FC480894A6 Q33653686-00695E69-BD16-4653-B086-64B8A3090F79 Q33728905-A1B1F019-E6E4-4D86-A72A-9FD40E515E5C Q33779587-CBAF50C1-5540-4D6A-ABC5-0E978B680D09 Q33953620-35A136DC-7611-4DA2-AB3B-723BCD19C840 Q33959946-FBE38BDC-8971-4B3F-878E-DB05B62300A8 Q34046490-C2BA3E32-039F-4F88-8A5C-A9526264CB5D Q34143477-0DE8EF72-8FBB-4E7D-805F-DA4C4BFFCC1B Q34149078-CBFF2D26-7254-4704-88B8-53D0138A01B0

P2860

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

http://www.wikidata.org/entity/Q33926467

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

@ast

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

@en

type

label

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

@ast

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

@en

prefLabel

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

@ast

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

@en

P1433

Q33926467-10692AB0-FF3C-4CEB-8DD4-E0B40D7FC6A7

P1476

Q33926467-21C055EA-6624-440E-A7CC-A098E1C7B5B2

P2093

Q33926467-7481FB04-56A7-4D43-8A02-DF2253F3CE45

Q33926467-9D004A2A-443F-4E51-9158-B8C8BBC172A9

P2860

Q33926467-01B65D11-5592-44D0-B91E-F8ED828944A8

Q33926467-02717539-00D1-4547-BB51-2F2D1A5C0998

Q33926467-0B640BEF-7945-40BC-9D83-F23834EEC3B3

Q33926467-0B99C34A-EC6A-429D-AF38-44E4C14D3B58

Q33926467-0C3304A1-A98B-4BE4-A13D-D836244D9F36

Q33926467-0C7DF3A9-F7AC-42F8-813F-A98B8A598AC3

Q33926467-1061CE70-C26E-4C28-9C69-722C29A7C6D4

Q33926467-10B6E60D-D2EC-40F4-AA8B-B4B3D34E1CE6

Q33926467-14FEE2C7-48BD-4169-AB86-BA59BEEE1193

Q33926467-162B7057-7B24-4AFD-BE23-919F4CA01DE9

P2888

Q33926467-279B5A70-1EC6-40E6-8102-8DD2B0E430E6

P304

Q33926467-33B61313-B210-4EF5-AFF7-8BF08187038E

P31

Q33926467-C2D5AE8D-6E21-4C84-9588-A3782000F186

P356

Q33926467-63C83009-961D-4381-A661-F5218A340D47

P407

Q33926467-B05B1E61-D5CC-46B7-BD0E-8BFFD691FBE4

P433

Q33926467-371CB414-E458-4E6A-A015-6D5865059B5A

P478

Q33926467-13937F97-0B0F-447C-A88F-6DC17DCC8784

P50

Q33926467-0D6C4FF6-2DBD-407E-BB1F-47193F4194A8

P577

Q33926467-C5FACE0A-0AE7-4582-8BBA-4EE358CBA174

P5875

Q33926467-7AE2D6D3-F229-47F2-BCD3-605AA277F991

P6179

Q33926467-17E40557-5416-4060-980B-11EAE778AA30

P698

Q33926467-35C13569-F886-43FA-891E-45BFB4B4B991

P932

Q33926467-7204CE1F-17E4-4697-9106-9E6F51048CE4

P356

P1433

Nature Reviews Cancer

P1476

Mitotic chromosomal instability and cancer: mouse modelling of the human disease

@en

P2093

Juan-Manuel Schvartzman

http://www.w3.org/2001/XMLSchema#string

Robert Benezra

http://www.w3.org/2001/XMLSchema#string

P2860

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

Identification of a human mitotic checkpoint gene: hsMAD2

Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint

Mutations of mitotic checkpoint genes in human cancers

BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis.

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer

Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero

P2888

P304

102-115

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NRC2781

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41112118

http://www.w3.org/2001/XMLSchema#string

P6179

1041793251

http://www.w3.org/2001/XMLSchema#string

P698

20094045

http://www.w3.org/2001/XMLSchema#string

P932

5526619

http://www.w3.org/2001/XMLSchema#string