Conserved loop I of U5 small nuclear RNA is dispensable for both catalytic steps of pre-mRNA splicing in HeLa nuclear extracts.
about
Prp8 protein: at the heart of the spliceosomePSF and p54nrb bind a conserved stem in U5 snRNAAssembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain.Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing.The carboxy terminal WD domain of the pre-mRNA splicing factor Prp17p is critical for function.ATP-dependent interaction of yeast U5 snRNA loop 1 with the 5' splice site.A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formationRNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core.5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly.A general approach for identification of RNA-protein cross-linking sites within native human spliceosomal small nuclear ribonucleoproteins (snRNPs). Analysis of RNA-protein contacts in native U1 and U4/U6.U5 snRNPs.Mutations in U5 snRNA loop 1 influence the splicing of different genes in vivo.Genetic and functional interaction of evolutionarily conserved regions of the Prp18 protein and the U5 snRNA.The RNA splicing factor hSlu7 is required for correct 3' splice-site choice.Proximity of the invariant loop of U5 snRNA to the second intron residue during pre-mRNA splicing.A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast.Identification of a U2/U6 helix la mutant that influences 3' splice site selection during nuclear pre-mRNA splicing.Single-molecule analysis of protein-free U2-U6 snRNAs.Functionally important structural elements of U12 snRNACorrelated Evolution of Nucleotide Positions within Splice Sites in Mammals.How did alternative splicing evolve?Functional roles of protein splicing factors."Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.Splicing of mRNA precursors: the role of RNAs and proteins in catalysis.The mechanism of the second step of pre-mRNA splicing.Sequences upstream of the branch site are required to form helix II between U2 and U6 snRNA in a trans-splicing reaction.Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing.Evolution of small nuclear RNAs in S. cerevisiae, C. albicans, and other hemiascomycetous yeasts.Comparative analysis detects dependencies among the 5' splice-site positions.Multiple functions for the invariant AGC triad of U6 snRNA.Genome-wide profiling of mouse RNA secondary structures reveals key features of the mammalian transcriptome.Post-transcriptional modifications modulate conformational dynamics in human U2-U6 snRNA complex.Splicing-related catalysis by protein-free snRNAs.Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation.
P2860
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P2860
Conserved loop I of U5 small nuclear RNA is dispensable for both catalytic steps of pre-mRNA splicing in HeLa nuclear extracts.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@ast
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@en
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@en-gb
type
label
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@ast
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@en
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@en-gb
prefLabel
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@ast
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@en
Conserved loop I of U5 small n ...... cing in HeLa nuclear extracts.
@en-gb
P2093
P2860
P356
P1476
Conserved loop I of U5 small n ...... icing in HeLa nuclear extracts
@en
P2093
C Branlant
M Polycarpou-Schwarz
R Lührmann
P2860
P304
P356
10.1128/MCB.19.4.2782
P407
P577
1999-04-01T00:00:00Z