Metformin improves healthspan and lifespan in mice. - Test2 - elhamkhani - TriplyDB

Metformin improves healthspan and lifespan in mice.

Metformin improves healthspan and lifespan in mice.

http://www.wikidata.org/entity/Q34360789

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Repurposing metformin: an old drug with new tricks in its binding pockets Epigenetics and aging Insulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycle Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Geroscience approaches to increase healthspan and slow aging Reprogramming of energy metabolism as a driver of aging Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic Current understanding of metformin effect on the control of hyperglycemia in diabetes Caloric restriction and exercise "mimetics'': Ready for prime time?Biochemical Genetic Pathways that Modulate Aging in Multiple Species New mechanisms of metformin action: Focusing on mitochondria and the gut MYC, Metabolism, and Cancer Exenatide once-weekly injection for the treatment of type 2 diabetes in Chinese patients: current perspectives Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction Mitohormesis The search for antiaging interventions: from elixirs to fasting regimens New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart Something old, something new and something very old: drugs for treating type 2 diabetes You are what you host: microbiome modulation of the aging process Metformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the Endothelium Obesity, metabolic syndrome, and airway disease: a bioenergetic problem?Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency Worms, bacteria, and micronutrients: an elegant model of our diet Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import Reduced expression of MYC increases longevity and enhances healthspan.Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disorders MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism The C. elegans model in toxicity testing Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan Aging and adipose tissue: potential interventions for diabetes and regenerative medicine Metformin and metabolic diseases: a focus on hepatic aspects The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds Metformin protects skeletal muscle from cardiotoxin induced degeneration Metformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived Xenografts Resveratrol Reverses Functional Chagas Heart Disease in Mice Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons Metformin as a cellular protector; a synoptic view of modern evidences

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Metformin improves healthspan and lifespan in mice.

http://www.wikidata.org/entity/Q34360789

description

2013 nî lūn-bûn

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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Metformin improves healthspan and lifespan in mice.

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Metformin improves healthspan and lifespan in mice.

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Metformin improves healthspan and lifespan in mice.

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Metformin improves healthspan and lifespan in mice.

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Metformin improves healthspan and lifespan in mice.

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Metformin improves healthspan and lifespan in mice.

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Metformin improves healthspan and lifespan in mice.

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Metformin improves healthspan and lifespan in mice.

@en

Metformin improves healthspan and lifespan in mice.

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Nature Communications

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Metformin improves healthspan and lifespan in mice.

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Alejandro Martin-Montalvo

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Ana P Gomes

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Donald K Ingram

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Evi M Mercken

http://www.w3.org/2001/XMLSchema#string

Hector H Palacios

http://www.w3.org/2001/XMLSchema#string

Marie-José Blouin

http://www.w3.org/2001/XMLSchema#string

Matthias Schwab

http://www.w3.org/2001/XMLSchema#string

Michael Pollak

http://www.w3.org/2001/XMLSchema#string

Norman S Wolf

http://www.w3.org/2001/XMLSchema#string

Patricia L Mote

http://www.w3.org/2001/XMLSchema#string

P2860

Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase-Dependent Regulation of the Orphan Nuclear Receptor SHP

Role of AMP-activated protein kinase in mechanism of metformin action

Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms

Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

PAGE: parametric analysis of gene set enrichment

Investigating metformin for cancer prevention and treatment: the end of the beginning

Diabetes and cancer: a consensus report.

Resveratrol improves health and survival of mice on a high-calorie diet

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2192

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10.1038/NCOMMS3192

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4

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Kevin G. Becker

Morten Scheibye-Knudsen

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2013-01-01T00:00:00Z

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253647401

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23900241

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3736576

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