Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
about
The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changesEnvisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairInvolvement of DNA damage response pathways in hepatocellular carcinoma.The actin depolymerizing factor (ADF)/cofilin signaling pathway and DNA damage responses in cancerFunctional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil DomainProcessing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.Histone acetyltransferase 1 promotes homologous recombination in DNA repair by facilitating histone turnover.Gingival fibroblasts resist apoptosis in response to oxidative stress in a model of periodontal diseases.The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.Repair of double-strand breaks by end joining.RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress.Post-translational methylations of the archaeal Mre11:Rad50 complex throughout the DNA damage response.The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
P2860
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P2860
Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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name
Rad50 zinc hook is important f ...... various DNA damage responses.
@ast
Rad50 zinc hook is important f ...... various DNA damage responses.
@en
type
label
Rad50 zinc hook is important f ...... various DNA damage responses.
@ast
Rad50 zinc hook is important f ...... various DNA damage responses.
@en
prefLabel
Rad50 zinc hook is important f ...... various DNA damage responses.
@ast
Rad50 zinc hook is important f ...... various DNA damage responses.
@en
P2093
P2860
P356
P1476
Rad50 zinc hook is important f ...... various DNA damage responses.
@en
P2093
Alejandro Negrete
Chi-Sheng Lu
Joseph Shiloach
Lan N Truong
Linda Z Shi
Michael W Berns
Niema Razavian
Xiaohua Wu
Yongjiang Li
P2860
P304
31747-31756
P356
10.1074/JBC.M112.384750
P407
P577
2012-07-25T00:00:00Z