Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells.
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Metabolic, autophagic, and mitophagic activities in cancer initiation and progressionEstablishment and Maintenance of the Human Naïve CD4+ T-Cell CompartmentMechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer ImmunotherapyCytosolic sequestration of Prep1 influences early stages of T cell development.Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells.Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repressionAn overview of IL-7 biology and its use in immunotherapy.Evidence of STAT5-dependent and -independent routes to CD8 memory formation and a preferential role for IL-7 over IL-15 in STAT5 activationFoxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.Interleukin-7 mediates glucose utilization in lymphocytes through transcriptional regulation of the hexokinase II geneFOXO3 regulates CD8 T cell memory by T cell-intrinsic mechanisms.Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.Intracellular insulin-like growth factor-1 induces Bcl-2 expression in airway epithelial cellsFOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma.Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.IL-7 is essential for homeostatic control of T cell metabolism in vivoInterleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanismsExpression of interleukins 7 & 8 in peripheral blood mononuclear cells from patients with metabolic syndrome: a preliminary studyHighly specialized role of Forkhead box O transcription factors in the immune system.Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemiaImmunotherapeutic effects of IL-7 during a chronic viral infection in mice.Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells.High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling.PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells.Glut1-mediated glucose transport regulates HIV infection.Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection.Haematological malignancies: at the forefront of immunotherapeutic innovation.Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasmsIGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias.Autophagy in metazoans: cell survival in the land of plenty.HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes.Interleukin-7 in T-cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis?BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism.IL-7 promotes T cell proliferation through destabilization of p27Kip1.Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells.Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation.Interleukin 7 (IL-7) selectively promotes mouse and human IL-17-producing γδ cells.Effects of IL-7 on memory CD8 T cell homeostasis are influenced by the timing of therapy in mice
P2860
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P2860
Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Activation of PI3K is indispen ...... lymphoblastic leukemia cells.
@ast
Activation of PI3K is indispen ...... lymphoblastic leukemia cells.
@en
type
label
Activation of PI3K is indispen ...... lymphoblastic leukemia cells.
@ast
Activation of PI3K is indispen ...... lymphoblastic leukemia cells.
@en
prefLabel
Activation of PI3K is indispen ...... lymphoblastic leukemia cells.
@ast
Activation of PI3K is indispen ...... lymphoblastic leukemia cells.
@en
P2093
P2860
P921
P356
P1476
Activation of PI3K is indispen ...... lymphoblastic leukemia cells.
@en
P2093
Angelo A Cardoso
Joana G Brandao
Lee M Nadler
Vassiliki A Boussiotis
P2860
P304
P356
10.1084/JEM.20040789
P407
P577
2004-09-01T00:00:00Z