mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused. - Test2 - elhamkhani - TriplyDB

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

http://www.wikidata.org/entity/Q37929699

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The pivotal role of mammalian target of rapamycin inhibition in the treatment of patients with neuroendocrine tumors Differentiating mTOR inhibitors in renal cell carcinoma Integration of signals generated by nutrients, hormones, and exercise in skeletal muscle Pivotal role of mTORC2 and involvement of ribosomal protein S6 in cardioprotective signaling Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response.Mtor-Fanconi Anemia DNA Damage Repair Pathway in Cancer.Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer: a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING Potent dual inhibitors of TORC1 and TORC2 complexes (KU-0063794 and KU-0068650) demonstrate in vitro and ex vivo anti-keloid scar activity.Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome.mTORC2 mediates CXCL12-induced angiogenesis mTOR Inhibition: From Aging to Autism and Beyond.Time now to TORC the TORC? New developments in mTOR pathway inhibition in lymphoid malignancies.Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions Gβγ Pathways in Cell Polarity and Migration Linked to Oncogenic GPCR Signaling: Potential Relevance in Tumor Microenvironment.Rubella virus perturbs autophagy.Everolimus enhances gemcitabine-induced cytotoxicity in bladder-cancer cell lines.Localization of mTORC2 activity inside cells.Dynamic culture yields engineered myocardium with near-adult functional output.Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8.PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise.A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells.Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma.IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells.Thapsigargin induces apoptosis by impairing cytoskeleton dynamics in human lung adenocarcinoma cells.

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mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

http://www.wikidata.org/entity/Q37929699

description

article científic

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article scientifique

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articol științific

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articolo scientifico

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artigo científico

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artigo científico

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artigo científico

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artikel ilmiah

@id

artikull shkencor

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artículo científico

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name

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

@en

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

@nl

type

label

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

@en

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

@nl

prefLabel

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

@en

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

@nl

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mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused

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Evelyn Robles-Molina

http://www.w3.org/2001/XMLSchema#string

Ismael Bracho-Valdés

http://www.w3.org/2001/XMLSchema#string

Israel Valencia-Martínez

http://www.w3.org/2001/XMLSchema#string

Lydia Chávez-Vargas

http://www.w3.org/2001/XMLSchema#string

Paola Moreno-Alvarez

http://www.w3.org/2001/XMLSchema#string

P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

Activation of mTORC2 by association with the ribosome

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

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896-914

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scholarly article

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10.1002/IUB.558

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10

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63

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Jose Vazquez-prado

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2011-09-09T00:00:00Z

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230217636

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21905202

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