about
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCPE1-L2 activates both ubiquitin and FAT10Human metapneumovirus M2-2 protein inhibits innate cellular signaling by targeting MAVST cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20Peroxisomes are signaling platforms for antiviral innate immunityMAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune responseRNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathwayCyclic di-GMP sensing via the innate immune signaling protein STINGThe TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytesA host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMPPellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activationPrion-like polymerization as a signaling mechanismCyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STINGIdentification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chainsMurine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replicationHSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signalingUbiquitin signalling in the NF-kappaB pathwayPivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination.NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKKSTING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathwayThe cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling.Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.Essential role of TAK1 in thymocyte development and activation.Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitisMolecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING.Differential roles for RIG-I-like receptors and nucleic acid-sensing TLR pathways in controlling a chronic viral infection.TRAF2: a double-edged sword?Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems.Getting to grips with hepatitis.Antiviral innate immunity pathways.Sorting out Toll signals.RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge.Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor.Ubiquitin in NF-kappaB signaling.
P50
Q21666110-D4337353-1855-4E0D-9454-A59DE97C383DQ24294748-E2E26F09-A91B-456C-85C4-AEEE8E081F81Q24299636-E7969D07-FDB8-4CCC-900D-304C59AB4427Q24307779-7F57727A-F037-4958-8F8A-B86FF7B378C1Q24310723-55DCC5D0-D49F-45EE-B58E-A392A1B87112Q24316320-29E32D3A-D779-4E33-AF98-21264B1AC681Q24317317-DE826EB7-433A-42C1-A3D7-ADD461494CD6Q24338485-951D7118-B077-4D07-9C96-E68905190C9CQ24338639-50BE0EAF-33D3-49F0-9609-23B6C541C861Q24642631-928DA3F4-32C3-451F-8730-8A49650B19E5Q24653915-9EAB3326-EA0D-4FF0-A068-11847E6646D7Q26995776-DA76988F-2FC0-40AF-AF97-790D83A416D5Q27678540-D8AC938F-DC0E-4E0B-B2B6-E776AFCB8531Q27861127-19CCF022-A2B0-4ADD-96DA-38ED48B7A6FBQ28262399-25355C1B-869A-4078-8DAE-4ED30F8D3C35Q28278500-34E49961-0579-4803-B285-52BCAC1F46D1Q28474967-FB3992CD-B35E-42B2-AD08-239485D66BC4Q28477122-29CA79DC-C5FA-4F72-B0CA-4A22BD2E6909Q28508687-2083C0C4-71D5-411F-ABC3-10C27C01D97FQ29616322-91F0EF5C-C691-450C-A544-7ED5F5FDA06BQ33767456-56E6EE51-80F5-435C-A5C5-48B521924C78Q34027440-96AB58CF-DF29-4DD2-96E3-E951CBFAD13BQ34259150-8812C2AA-3BDE-41BC-8204-82A02DFA6B30Q34417115-8E0238B3-CC88-42B1-861B-6A1F12DA0297Q34745565-759EB9CD-84BF-4978-831C-939E622CD9E8Q34984483-1EBB7F9A-068A-4DAE-9179-8270FEBDA2E4Q35164770-30626FA4-3AF0-4827-9E69-FE53E3689A82Q35240439-147AE727-8867-4ACE-BEB7-8EB7067633D0Q35409347-9B03684A-D387-41CD-870E-6B043E2FF102Q35895670-3AEACCDA-2AD2-460D-9439-B5051D2C7576Q35903286-4E345690-88DF-440C-AE10-275C523EF9B3Q36053266-39F221D2-786E-4487-BE67-62508DC898BDQ36315245-69743AF5-1788-49F5-AC0A-DD18D3D4C732Q36361478-C57B46CA-E632-4B57-898F-56BADC3B8512Q36394971-87646802-D479-48B3-B4D1-6BF6854AF9A5Q36496439-58567073-063B-4CD6-A89D-58B4D247098FQ36759999-70780D97-910A-4926-A936-E47C62A46A6AQ36791049-6A143CC2-24FB-44F9-B40D-F78838284346Q36842242-B6239302-7B63-41AD-9AA0-7DC2153C36DAQ37327225-40E524FC-690D-401E-B72E-EE636B6A1AED
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Zhijian J Chen
@ast
Zhijian J Chen
@en
Zhijian J Chen
@es
Zhijian J Chen
@nl
type
label
Zhijian J Chen
@ast
Zhijian J Chen
@en
Zhijian J Chen
@es
Zhijian J Chen
@nl
prefLabel
Zhijian J Chen
@ast
Zhijian J Chen
@en
Zhijian J Chen
@es
Zhijian J Chen
@nl
P106
P1153
7409487227
P31
P496
0000-0002-8475-8251