mTOR-dependent signalling in Alzheimer's disease - Wikidata - wikimedia - TriplyDB

mTOR-dependent signalling in Alzheimer's disease

mTOR-dependent signalling in Alzheimer's disease

http://www.wikidata.org/entity/Q28308319

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Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Alzheimer's Disease: Mechanism and Approach to Cell Therapy The neurology of mTOR Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin Consolidation and translation regulation Tau and tauopathies Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease The role of mTOR signaling in Alzheimer disease The zinc dyshomeostasis hypothesis of Alzheimer's disease Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer disease Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in mice Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature mTORC1 Is a Local, Postsynaptic Voltage Sensor Regulated by Positive and Negative Feedback Pathways.Cotinine halts the advance of Alzheimer's disease-like pathology and associated depressive-like behavior in Tg6799 mice Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.Concerted perturbation observed in a hub network in Alzheimer's disease Elucidating the role of DEPTOR in Alzheimer's disease.Finding undetected protein associations in cell signaling by belief propagation.Hot topics in aging research: protein translation and TOR signaling, 2010 Frontier of epilepsy research - mTOR signaling pathway.Phospholipase D in brain function and Alzheimer's disease.Effect of treadmill exercise on PI3K/AKT/mTOR, autophagy, and Tau hyperphosphorylation in the cerebral cortex of NSE/htau23 transgenic mice Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases Analysis of Proteins That Rapidly Change Upon Mechanistic/Mammalian Target of Rapamycin Complex 1 (mTORC1) Repression Identifies Parkinson Protein 7 (PARK7) as a Novel Protein Aberrantly Expressed in Tuberous Sclerosis Complex (TSC)mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats Dysfunction of the mTOR pathway is a risk factor for Alzheimer's disease.PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging Cerebral mTOR signal and pro-inflammatory cytokines in Alzheimer's disease rats.Mitophagy and Parkinson's disease: the PINK1-parkin link.Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization.Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease.Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology Rapamycin inhibits lipopolysaccharide-induced neuroinflammation in vitro and in vivo.Molecular mechanisms linking diabetes mellitus and Alzheimer disease: beta-amyloid peptide, insulin signaling, and neuronal function.Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?Roles of AMP-activated protein kinase in Alzheimer's disease.Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease.

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mTOR-dependent signalling in Alzheimer's disease

http://www.wikidata.org/entity/Q28308319

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

mTOR-dependent signalling in Alzheimer's disease

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mTOR-dependent signalling in Alzheimer's disease

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mTOR-dependent signalling in Alzheimer's disease

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type

label

mTOR-dependent signalling in Alzheimer's disease

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mTOR-dependent signalling in Alzheimer's disease

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mTOR-dependent signalling in Alzheimer's disease

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prefLabel

mTOR-dependent signalling in Alzheimer's disease

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mTOR-dependent signalling in Alzheimer's disease

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mTOR-dependent signalling in Alzheimer's disease

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J.1582-4934.2008.00509.X

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Journal of Cellular and Molecular Medicine

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mTOR-dependent signalling in Alzheimer's disease

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Jin-Jing Pei

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P2860

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

TOR signaling in growth and metabolism

Molecular organization of target of rapamycin complex 2.

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau

mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain

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Alzheimer's disease

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