Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations
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Protein phosphatase 2A dysfunction in Alzheimer's diseaseProtein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complexPhysiological and pathological phosphorylation of tau by Cdk5The role of tau in neurodegenerative diseases and its potential as a therapeutic targetTau and tauopathiesIncreased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalitiesOxidative stress promotes autophagic cell death in human neuroblastoma cells with ectopic transfer of mitochondrial PPP2R2B (Bbeta2).Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function.Multiplex three-dimensional brain gene expression mapping in a mouse model of Parkinson's disease.The cytoskeleton in neurodegenerative diseases.The protein phosphatase PP2A/Bα binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies.Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies?Tau alternative splicing and frontotemporal dementia.Tau phosphorylation and aggregation in Alzheimer's disease pathology.Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?Pin1 has opposite effects on wild-type and P301L tau stability and tauopathyTau phosphorylation, aggregation, and cell toxicityCase records of the Massachusetts General Hospital. Case 9-2015. A 31-year-old man with personality changes and progressive neurologic decline.Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps.Tau mutations in neurodegenerative diseases.Chronic consumption of Annona muricata juice triggers and aggravates cerebral tau phosphorylation in wild-type and MAPT transgenic mice.Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits.Differential autophagic cell death under stress with ectopic cytoplasmic and mitochondrial-specific PPP2R2B in human neuroblastoma cells.New routes in frontotemporal dementia drug discovery.Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cellsExpression of protein phosphatase 2A mutants and silencing of the regulatory B alpha subunit induce a selective loss of acetylated and detyrosinated microtubules.Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model.MRNA Levels of ACh-Related Enzymes in the Hippocampus of THY-Tau22 Mouse: A Model of Human Tauopathy with No Signs of Motor Disturbance.Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'.Pick's disease associated with the novel Tau gene mutation K369I.Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation.Untangling Tau and Iron: Exploring the Interaction Between Iron and Tau in Neurodegeneration
P2860
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P2860
Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations
description
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
scientific journal article
@en
vedecký článok (publikovaný 2000/11/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/11/01)
@nl
наукова стаття, опублікована в листопаді 2000
@uk
مقالة علمية (نشرت في نوفمبر 2000)
@ar
name
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@ast
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@en
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@nl
type
label
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@ast
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@en
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@nl
prefLabel
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@ast
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@en
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@nl
P2093
P2860
P921
P1476
Reduced binding of protein pho ...... ked to chromosome 17 mutations
@en
P2093
C. Kamibayashi
C. L. White
M. Goedert
M. J. Smith
S. Satumtira
P2860
P304
P356
10.1046/J.1471-4159.2000.0752155.X
P407
P577
2000-11-01T00:00:00Z