Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation. - Wikidata - wikimedia - TriplyDB

Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.

Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.

http://www.wikidata.org/entity/Q30439476

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Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation Targeting the mTOR signaling network for cancer therapy Cutting through the complexities of mTOR for the treatment of stroke mTOR-dependent cell survival mechanisms Regulation of mTORC1 by PI3K signaling Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin Nutrient regulation of the mTOR complex 1 signaling pathway Rag proteins regulate amino-acid-induced mTORC1 signalling.La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling Computational modeling and analysis of insulin induced eukaryotic translation initiation Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1)PRAS40 plays a pivotal role in protecting against stroke by linking the Akt and mTOR pathways Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.Enhancing mTOR-targeted cancer therapy.Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival TOR-dependent control of autophagy: biting the hand that feeds Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.PRAS40 regulates protein synthesis and cell cycle in C2C12 myoblasts.The complexes of mammalian target of rapamycin.The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age.mTOR signaling for biological control and cancer.Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway.Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors.Growing knowledge of the mTOR signaling network.SILAC-based quantitative proteomic analysis of human lung cell response to copper oxide nanoparticles.Frontier of epilepsy research - mTOR signaling pathway.Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signaling Deconvoluting mTOR biology Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling.Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes.A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.

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P2860

Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.

http://www.wikidata.org/entity/Q30439476

description

2008 nî lūn-bûn

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2008 թուականի Մարտին հրատարակուած գիտական յօդուած

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2008 թվականի մարտին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Regulation of proline-rich Akt ...... RC1)-mediated phosphorylation.

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Regulation of proline-rich Akt ...... RC1)-mediated phosphorylation.

@en

type

label

Regulation of proline-rich Akt ...... RC1)-mediated phosphorylation.

@ast

Regulation of proline-rich Akt ...... RC1)-mediated phosphorylation.

@en

prefLabel

Regulation of proline-rich Akt ...... RC1)-mediated phosphorylation.

@ast

Regulation of proline-rich Akt ...... RC1)-mediated phosphorylation.

@en

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P1433

Journal of Biological Chemistry

P1476

Regulation of proline-rich Akt ...... RC1)-mediated phosphorylation.

@en

P2093

John C Lawrence

http://www.w3.org/2001/XMLSchema#string

Lifu Wang

http://www.w3.org/2001/XMLSchema#string

Thurl E Harris

http://www.w3.org/2001/XMLSchema#string

P2860

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

TOR signaling in growth and metabolism

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies

Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor

P304

15619-15627

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scholarly article

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10.1074/JBC.M800723200

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23

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P478

283

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P577

2008-03-27T00:00:00Z

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18372248

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phosphorylation

P932

2414301

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