An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations.
about
Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH)Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndromeStructure of complement fragment C3b-factor H and implications for host protection by complement regulatorsComplement factor H and the hemolytic uremic syndromeExtended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implicationsMacular degeneration: recent advances and therapeutic opportunities.Age-related macular degeneration--emerging pathogenetic and therapeutic concepts.Favorable long-term outcome after liver-kidney transplant for recurrent hemolytic uremic syndrome associated with a factor H mutation.aHUS caused by complement dysregulation: new therapies on the horizon.Membrano-proliferative glomerulonephritis, atypical hemolytic uremic syndrome, and a new complement factor H mutation: report of a case.Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS).Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid.Dissection of functional sites in herpesvirus saimiri complement control protein homolog.Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration.Serum cystatin C level, kidney disease markers, and incidence of age-related macular degeneration: the Beaver Dam Eye Study.Complement factor H-derived short consensus repeat 18-20 enhanced complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia cells.New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3.Properdin and factor h: opposing players on the alternative complement pathway "see-saw".The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells.The Complement Inhibitor Factor H Generates an Anti-Inflammatory and Tolerogenic State in Monocyte-Derived Dendritic Cells.Structural and functional influences of coagulation factor XIII subunit B heterozygous missense mutants.Reduction of complement factor H binding to CLL cells improves the induction of rituximab-mediated complement-dependent cytotoxicity.Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H (CFH) gene family.Determination of complement factor H functional polymorphisms (V62I, Y402H, and E936D) using sequence-specific primer PCR and restriction fragment length polymorphisms.Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces
P2860
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P2860
An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
An interactive web database of ...... disease-associated mutations.
@ast
An interactive web database of ...... disease-associated mutations.
@en
type
label
An interactive web database of ...... disease-associated mutations.
@ast
An interactive web database of ...... disease-associated mutations.
@en
prefLabel
An interactive web database of ...... disease-associated mutations.
@ast
An interactive web database of ...... disease-associated mutations.
@en
P2093
P2860
P356
P1433
P1476
An interactive web database of ...... disease-associated mutations.
@en
P2093
Rebecca E Saunders
Stephen J Perkins
Timothy H J Goodship
P2860
P356
10.1002/HUMU.20268
P577
2006-01-01T00:00:00Z