Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation. - Wikidata - wikimedia - TriplyDB

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

http://www.wikidata.org/entity/Q33558779

about

Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1 SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint Structural determinants of the BRCA1 : estrogen receptor interaction The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathway DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains Highlight: BRCA1 and BRCA2 proteins in breast cancer NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks SOSS complexes participate in the maintenance of genomic stability Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation Multiple roles of ATM in monitoring and maintaining DNA integrity Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage Cdc7-Dbf4 and the human S checkpoint response to UVC Irofulven induces replication-dependent CHK2 activation related to p53 status Loss of Geminin induces rereplication in the presence of functional p53 Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function.BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM The Fanconi anaemia/BRCA pathway Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control Interaction of FANCD2 and NBS1 in the DNA damage response NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability The role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1 Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth

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Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

http://www.wikidata.org/entity/Q33558779

description

2001 nî lūn-bûn

@nan

2001 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի մայիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

@yue

name

Involvement of Brca1 in S-phase and G

@nl

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

@ast

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

@en

type

label

Involvement of Brca1 in S-phase and G

@nl

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

@ast

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

@en

prefLabel

Involvement of Brca1 in S-phase and G

@nl

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

@ast

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

@en

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MCB.21.10.3445-3450.2001

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Molecular and Cellular Biology

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Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

@en

P2093

B Xu

http://www.w3.org/2001/XMLSchema#string

Kim St

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M B Kastan

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P2860

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

Genetic analysis of BRCA1 function in a defined tumor cell line

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

In search of the tumour-suppressor functions of BRCA1 and BRCA2

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3445-3450

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10.1128/MCB.21.10.3445-3450.2001

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12022237

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11313470

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100266

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