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Altered thymic positive selection and intracellular signals in Cbl-deficient mice

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

http://www.wikidata.org/entity/Q33596728

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Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130 Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells E3 ubiquitin ligases and their control of T cell autoreactivity Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte Negative regulation of Lck by Cbl ubiquitin ligase The Cbl interactome and its functions Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3 The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.Murine Schnurri-2 is required for positive selection of thymocytes Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation DLGH1 is a negative regulator of T-lymphocyte proliferation Regulation of T cell development by the deubiquitinating enzyme CYLD A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin.The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.c-Cbl-mediated regulation of LAT-nucleated signaling complexes Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding.CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.Role of c-Cbl-dependent regulation of phospholipase Cgamma1 activation in experimental choroidal neovascularization Adapter molecules in T cell receptor signaling.Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.Organization of proximal signal initiation at the TCR:CD3 complex.Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune disease Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.

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P2860

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

http://www.wikidata.org/entity/Q33596728

description

1998 nî lūn-bûn

@nan

1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

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1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

@ast

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

@en

type

label

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

@ast

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

@en

prefLabel

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

@ast

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

@en

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

@en

P2093

H Gu

http://www.w3.org/2001/XMLSchema#string

H K Kole

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R J Hu

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P2860

Essential role for ZAP-70 in both positive and negative selection of thymocytes

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

FYVE fingers bind PtdIns(3)P

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development

T cell receptor antagonist peptides induce positive selection

Signal transduction by lymphocyte antigen receptors

D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites.

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