Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase. - Wikidata - wikimedia - TriplyDB

Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase.

Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase.

http://www.wikidata.org/entity/Q33968074

about

MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases An expression screen reveals modulators of class II histone deacetylase phosphorylation The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization Characterization of gene expression induced by RET with MEN2A or MEN2B mutation Leukaemia inhibitory factor (LIF) is functionally linked to axotrophin and both LIF and axotrophin are linked to regulatory immune tolerance The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold.Altered gene expression in highly purified enterocytes from patients with active coeliac disease.Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.Regulation of glucose homeostasis by KSR1 and MARK2.Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis.mTOR signaling, Tregs and immune modulation.mTOR Links Environmental Signals to T Cell Fate Decisions.Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo Immunotoxicity of β-Diketone Antibiotic Mixtures to Zebrafish (Danio rerio) by Transcriptome Analysis.MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton.Inactivation of MARK4, an AMP-activated protein kinase (AMPK)-related kinase, leads to insulin hypersensitivity and resistance to diet-induced obesity Extending from PARs in Caenorhabditis elegans to homologues in Haemonchus contortus and other parasitic nematodes.Derepression of pathological cardiac genes by members of the CaM kinase superfamily.Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division.New insights into the molecular mechanisms specifying neuronal polarity in vivo Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates.Fas expression on antigen-specific T cells has costimulatory, helper, and down-regulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses.Role of partitioning-defective 1/microtubule affinity-regulating kinases in the morphogenetic activity of Helicobacter pylori CagA.Phosphorylation of the E3 ubiquitin ligase RNF41 by the kinase Par-1b is required for epithelial cell polarity.Identification of Candidate Genes Related to Inflammatory Bowel Disease Using Minimum Redundancy Maximum Relevance, Incremental Feature Selection, and the Shortest-Path Approach.Understanding the structure and function of the immunological synapse Cellular polarity in aging: role of redox regulation and nutrition.Polarized cells, polarized views: asymmetric cell division in hematopoietic cells.The polarity-inducing kinase Par-1 controls Xenopus gastrulation in cooperation with 14-3-3 and aPKC.Regulation of Cell Polarity by PAR-1/MARK Kinase.Partitioning-Defective 1a/b Depletion Impairs Glomerular and Proximal Tubule Development.LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro.Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways.Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis.Metabolic control of regulatory T cell (Treg) survival and function by Lkb1.

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Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase.

http://www.wikidata.org/entity/Q33968074

description

2001 nî lūn-bûn

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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2001 թվականի մայիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Immune system dysfunction and ...... ng Emk (Par-1) protein kinase.

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Immune system dysfunction and ...... ng Emk (Par-1) protein kinase.

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Immune system dysfunction and ...... ng Emk (Par-1) protein kinase.

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Immune system dysfunction and ...... ng Emk (Par-1) protein kinase.

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Immune system dysfunction and ...... ng Emk (Par-1) protein kinase.

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Immune system dysfunction and ...... ng Emk (Par-1) protein kinase.

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MCB.21.9.3206-3219.2001

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Molecular and Cellular Biology

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Immune system dysfunction and ...... ing Emk (Par-1) protein kinase

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Chan AC

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Hurov JB

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Murphy KM

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Piwnica-Worms H

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Ranganath SH

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Stappenbeck TS

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White LS

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Zmasek CM

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P2860

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

Essential role for ZAP-70 in both positive and negative selection of thymocytes

Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

Human serine/threonine protein kinase EMK1: genomic structure and cDNA cloning of isoforms produced by alternative splicing

Requirement for B cell linker protein (BLNK) in B cell development

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding

par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

PARsing embryonic polarity.

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3206-3219

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10.1128/MCB.21.9.3206-3219.2001

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9

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21

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John H. Russell

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2001-05-01T00:00:00Z

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11287624

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86958

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