Generation and characterization of Smac/DIABLO-deficient mice. - Wikidata - wikimedia - TriplyDB

Generation and characterization of Smac/DIABLO-deficient mice.

Generation and characterization of Smac/DIABLO-deficient mice.

http://www.wikidata.org/entity/Q34279589

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HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53 No death without life: vital functions of apoptotic effectors Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9 SMAC is expressed de novo in a subset of cervical cancer tumors Regulation of Cell Death by IAPs and Their Antagonists Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events Smac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathway Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis Dynamic changes of the anti- and pro-apoptotic proteins Bcl-w, Bcl-2, and Bax with Smac/Diablo mitochondrial release after photothrombotic ring stroke in rats Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injury The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway.Generation and characterization of the Anp32e-deficient mouse TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence.Coupling of caspase-9 to Apaf1 in response to loss of pRb or cytotoxic drugs is cell-type-specific.Sept4/ARTS is required for stem cell apoptosis and tumor suppression.Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.A time to kill: targeting apoptosis in cancer.Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools.The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo.The mitochondrial death pathway: a promising therapeutic target in diseases Non-apoptotic functions of apoptosis-regulatory proteins.Cell differentiation: reciprocal regulation of Apaf-1 and the inhibitor of apoptosis proteins.XIAP activity dictates Apaf-1 dependency for caspase 9 activation.Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death The role of mitochondria in apoptosis*.Therapeutic targets in the mitochondrial apoptotic pathway.Regulation of apoptosis by XIAP ubiquitin-ligase activity Inhibitor of apoptosis proteins as targets for anticancer therapy.Regulation of apoptosis in Drosophila.Living with death: the evolution of the mitochondrial pathway of apoptosis in animals.Differential regulation of Smac/DIABLO and Hsp-70 during brain maturation

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Generation and characterization of Smac/DIABLO-deficient mice.

http://www.wikidata.org/entity/Q34279589

description

2002 nî lūn-bûn

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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2002 թվականի մայիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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name

Generation and characterization of Smac/DIABLO-deficient mice.

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Generation and characterization of Smac/DIABLO-deficient mice.

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Generation and characterization of Smac/DIABLO-deficient mice.

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type

label

Generation and characterization of Smac/DIABLO-deficient mice.

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Generation and characterization of Smac/DIABLO-deficient mice.

@en

Generation and characterization of Smac/DIABLO-deficient mice.

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prefLabel

Generation and characterization of Smac/DIABLO-deficient mice.

@ast

Generation and characterization of Smac/DIABLO-deficient mice.

@en

Generation and characterization of Smac/DIABLO-deficient mice.

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MCB.22.10.3509-3517.2002

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Molecular and Cellular Biology

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Generation and characterization of Smac/DIABLO-deficient mice

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Andrew Elia

http://www.w3.org/2001/XMLSchema#string

Andrew Wakeham

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Annick Itie

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Chunying Du

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Gordon S Duncan

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Hitoshi Okada

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Jianping Jin

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Scott W Lowe

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Tak W Mak

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Xiaodong Wang

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P2860

Molecular characterization of mitochondrial apoptosis-inducing factor

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs.

Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

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3509-3517

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scholarly article

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10.1128/MCB.22.10.3509-3517.2002

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10

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Woong-Kyung Suh

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2002-05-01T00:00:00Z

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11971981

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133802

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