Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.
about
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophyRemoval of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmiasDysfunctional ryanodine receptors in the heart: new insights into complex cardiovascular diseasesModulation of cardiac contractility by the phospholamban/SERCA2a regulatomePhosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmiasEnhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure.K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulumRemodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacityK201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 associationThe ryanodine receptor leak: how a tattered receptor plunges the failing heart into crisisDefective interactions of protein partner with ion channels and transporters as alternative mechanisms of membrane channelopathiesMechanisms of altered Ca²⁺ handling in heart failureGene therapy targets in heart failure: the path to translationA network-oriented perspective on cardiac calcium signalingInherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesisAnalysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in miceRole of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunctionEffect of Calstabin1 depletion on calcium transients and energy utilization in muscle fibers and treatment opportunities with RyR1 stabilizersDirect association of the reticulon protein RTN1A with the ryanodine receptor 2 in neuronsEstrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmiasModulation of CaV1.2 channels by Mg2+ acting at an EF-hand motif in the COOH-terminal domainLeaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice.Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.Bradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia riskAerobic interval training partly reverse contractile dysfunction and impaired Ca2+ handling in atrial myocytes from rats with post infarction heart failureIdentification of novel missense mutations of cardiac ryanodine receptor gene in exercise-induced sudden death at autopsy.The molecular basis of catecholaminergic polymorphic ventricular tachycardia: what are the different hypotheses regarding mechanisms?Search for cardiac calcium cycling gene mutations in familial ventricular arrhythmias resembling catecholaminergic polymorphic ventricular tachycardia.Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments.Dysregulated sarcoplasmic reticulum calcium release: potential pharmacological target in cardiac disease.Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease.Development of electrocardiogram intervals during growth of FVB/N neonate mice.Altered intracellular Ca2+ handling in heart failure.Genetic causes of human heart failure.Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Ryanodine receptor channelopathies.Mechanisms of sudden cardiac death.Cardiac ryanodine receptor phosphorylation: target sites and functional consequencesArrhythmogenic right ventricular cardiomyopathy in Boxer dogs is associated with calstabin2 deficiency.
P2860
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P2860
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@ast
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@en
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@nl
type
label
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@ast
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@en
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@nl
prefLabel
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@ast
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@en
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@nl
P2093
P356
P1433
P1476
Protection from cardiac arrhyt ...... tabilizing protein calstabin2.
@en
P2093
Andrew R Marks
Daniel Cervantes
Donald W Landry
James Coromilas
John A Vest
Shi-Xian Deng
Stephan E Lehnart
Steven R Reiken
P304
P356
10.1126/SCIENCE.1094301
P407
P577
2004-04-01T00:00:00Z