Herpes simplex virus immediate-early protein ICP22 is required for viral modification of host RNA polymerase II and establishment of the normal viral transcription program.
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ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 geneHerpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells.A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infectionFunctional anatomy of herpes simplex virus 1 overlapping genes encoding infected-cell protein 22 and US1.5 proteinA novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory proteinAssociation of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzymeRoscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factorsBovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting ApoptosisA comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivationThe EICP22 protein of equine herpesvirus 1 physically interacts with the immediate-early protein and with itself to form dimers and higher-order complexesHerpes simplex virus type 1 immediate-early protein ICP22 is required for VICE domain formation during productive viral infection.Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodiesVirus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infectionTranscription of herpes simplex virus immediate-early and early genes is inhibited by roscovitine, an inhibitor specific for cellular cyclin-dependent kinasesRole of herpes simplex virus 1 immediate early protein ICP22 in viral nuclear egress.Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins.The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growthThe carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1.ICP22 and the UL13 protein kinase are both required for herpes simplex virus-induced modification of the large subunit of RNA polymerase II.Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0.Posttranslational processing of infected cell protein 22 mediated by viral protein kinases is sensitive to amino acid substitutions at distant sites and can be cell-type specificHerpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functionsHerpes simplex virus ICP27 activation of stress kinases JNK and p38.RNA polymerase II holoenzyme modifications accompany transcription reprogramming in herpes simplex virus type 1-infected cells.Mutational analysis of the repeated open reading frames, ORFs 63 and 70 and ORFs 64 and 69, of varicella-zoster virus.Herpes simplex virus type 1 infection leads to loss of serine-2 phosphorylation on the carboxyl-terminal domain of RNA polymerase II.HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis.Herpes simplex virus 1 ICP22 inhibits the transcription of viral gene promoters by binding to and blocking the recruitment of P-TEFbICP27 interacts with the C-terminal domain of RNA polymerase II and facilitates its recruitment to herpes simplex virus 1 transcription sites, where it undergoes proteasomal degradation during infection.The ICP22 protein selectively modifies the transcription of different kinetic classes of pseudorabies virus genes.Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcriptionHerpes simplex virus type 1 and bovine herpesvirus 1 latency.ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions.Sequence variation in the herpes simplex virus U(S)1 ocular virulence determinant.Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?The immediate-early 63 protein of Varicella-Zoster virus: analysis of functional domains required for replication in vitro and for T-cell and skin tropism in the SCIDhu model in vivo.Herpes simplex virus immediate-early protein ICP22 triggers loss of serine 2-phosphorylated RNA polymerase IIOverexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells.Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation.
P2860
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P2860
Herpes simplex virus immediate-early protein ICP22 is required for viral modification of host RNA polymerase II and establishment of the normal viral transcription program.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Herpes simplex virus immediate ...... l viral transcription program.
@ast
Herpes simplex virus immediate ...... l viral transcription program.
@en
type
label
Herpes simplex virus immediate ...... l viral transcription program.
@ast
Herpes simplex virus immediate ...... l viral transcription program.
@en
prefLabel
Herpes simplex virus immediate ...... l viral transcription program.
@ast
Herpes simplex virus immediate ...... l viral transcription program.
@en
P2093
P2860
P1433
P1476
Herpes simplex virus immediate ...... l viral transcription program.
@en
P2093
P2860
P304
P407
P577
1995-09-01T00:00:00Z