A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase.
about
FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptorsA mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brainTyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activationSignaling via Shc family adapter proteinsFunctional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptorsShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigenThe PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryoA novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytesA Drosophila analogue of v-Cbl is a dominant-negative oncoprotein in vivo.Role of Shc in T-cell development and function.Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivoThe carboxyl terminus of v-Abl protein can augment SH2 domain function.The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metalsSynergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso receptor tyrosine kinase.Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development.ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain.Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.Activation of the Drosophila C3G leads to cell fate changes and overproliferation during development, mediated by the RAS-MAPK pathway and RAP1.A novel Drosophila receptor tyrosine kinase expressed specifically in the nervous system. Unique structural features and implication in developmental signaling.Regulatory mechanisms of EGFR signalling during Drosophila eye development.Transmembrane glycoprotein gp150 is a substrate for receptor tyrosine phosphatase DPTP10D in Drosophila cells.Characterization of Drosophila insulin receptor substrate.Spatial signaling networks converge at the adaptor protein Shc.The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation.Interaction of the adaptor protein Shc and the adhesion molecule cadherin.Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.
P2860
Q24554326-B445CC13-BA05-484B-8DA1-AEC26A11DAF4Q24568236-76A36B22-50B7-420D-83FC-FF38C7B6476FQ24646756-9E839546-13A6-4BC3-A36C-4DAAF2DF7879Q28199357-57A0A40E-CD6C-4A9F-9619-CFCE768B07E1Q28306758-C9D40C0B-873A-47BF-A260-D9F535EAC204Q28364022-DC6AC0A2-5669-4DBC-B7C3-5A54E6D244DBQ28505266-27B65A0E-D9AC-47D6-885B-C34B5CF06ABFQ28586248-EAEE035A-F88D-4B62-BCE2-E584FA9937FFQ28609040-AACF4B73-17A3-4EDF-84F3-74107AD90377Q28616209-175939A1-DDE0-4AC8-A5E1-23575F307FF7Q30168862-16479838-0375-459D-93EB-1444D254AA3AQ30310587-F651033F-4DFD-484D-9486-0A0CD2CE6750Q30452658-3D92B4AB-F449-4FC4-A6DB-A6C3FC1C6AA3Q33804134-F224AC12-B5C1-468B-A6AD-2EE5EB3A69B9Q33968651-EAA686F4-62AB-48FB-82FF-F94627BF765EQ34819202-0347B70B-BFFF-470F-A2A2-FE4CD3EF9A0AQ34974027-B5A6564E-5560-4816-9185-83AFEA72BABDQ35872442-3BD66F78-3003-410E-894B-6C992CB75474Q36304091-689AE093-4602-4B7A-B33C-AA9224CCE2A7Q37725906-49863397-2D2A-4295-A223-5B233838F718Q38042699-DEB944D3-3863-48C7-BE52-5514B15E6FECQ38329782-F80EAEA6-D2A5-46E6-9C7D-33E582115352Q38346153-F28E3F58-8420-441E-94A4-87BE8181A7C5Q38758386-BAA03CDF-1A05-4D86-9F2B-18ED9FDC709CQ40023975-687211AA-66EB-4272-903C-01D35AF5C645Q40881261-DEC4A059-8AE4-4B26-A779-D533B6D025CEQ42411756-D5BE7E92-D8F2-4A88-A99D-294465FD9F58Q42797698-64E87FAF-B259-4F0D-A3A9-A94E367322FDQ42800627-EDD987AF-041C-4554-B3A8-F18BBF1139DFQ52551615-CC9137D2-15ED-4B4A-9ECB-9AF0C56BCF00
P2860
A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
A Drosophila shc gene product ...... DER receptor tyrosine kinase.
@ast
A Drosophila shc gene product ...... DER receptor tyrosine kinase.
@en
type
label
A Drosophila shc gene product ...... DER receptor tyrosine kinase.
@ast
A Drosophila shc gene product ...... DER receptor tyrosine kinase.
@en
prefLabel
A Drosophila shc gene product ...... DER receptor tyrosine kinase.
@ast
A Drosophila shc gene product ...... DER receptor tyrosine kinase.
@en
P2093
P2860
P356
P1476
A Drosophila shc gene product ...... DER receptor tyrosine kinase.
@en
P2093
P2860
P304
P356
10.1128/MCB.15.9.4810
P407
P577
1995-09-01T00:00:00Z