B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28.
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Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signalingCTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanismsCTLA-4 and PD-1 Pathways: Similarities, Differences, and Implications of Their InhibitionCo-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significanceImmune checkpoint blockade: a common denominator approach to cancer therapyUnifying concepts in CD28, ICOS and CTLA4 co-receptor signallingLack of impact of cytotoxic T-lymphocyte antigen 4 gene exon 1 polymorphism on susceptibility to or clinical course of egyptian childhood immune thrombocytopenic purpura.The role of CTLA-4 in the regulation of T cell immune responses.Cross-linking of CD80 on CD4+ T cells activates a calcium-dependent signaling pathwayMolecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.Interleukin-4-independent acceleration of cutaneous leishmaniasis in susceptible BALB/c mice following treatment with anti-CTLA4 antibody.CD28, CTLA-4 and their ligands: who does what and to whom?CTLA-4--the costimulatory molecule that doesn't: regulation of T-cell responses by inhibition.Interaction of CTLA-4 (CD152) with CD80 or CD86 inhibits human T-cell activation.Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.T-cell regulation by CD28 and CTLA-4.CTLA-4: new insights into its biological function and use in tumor immunotherapy.The soluble CTLA-4 splice variant protects from type 1 diabetes and potentiates regulatory T-cell functionPinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cellsCytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4(+) T cell responses.Enhancement of suboptimal CD8 cytotoxic T cell effector function in vivo using antigen-specific CD80 defective T cells.Role of T cell co-stimulation in murine models of allergic asthma.Antigen-specific blocking of CD4-specific immunological synapse formation using BPI and current therapies for autoimmune diseases.Association of B7-1 co-stimulation with the development of graft arterial disease. Studies using mice lacking B7-1, B7-2, or B7-1/B7-2.Challenges and future perspectives of T cell immunotherapy in cancerCTLA4 gene polymorphism and autoimmunity.Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity.Targeting the B7 family of co-stimulatory molecules: successes and challenges.CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic toleranceCostimulatory pathways: physiology and potential therapeutic manipulation in systemic lupus erythematosus.Immune checkpoint inhibitors for cancer treatment.Mechanistic and pharmacologic insights on immune checkpoint inhibitors.CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms.CTLA-4-Tg/CD-28-KO Mice Exhibit Reduced T Cell Proliferation in vivo Compared to CD-28-KO Mice in a Graft-versus-host Disease Model.Gene array and protein expression profiles suggest post-transcriptional regulation during CD8+ T cell differentiation.Differential roles of costimulatory signaling pathways in type 1 diabetes mellitus.CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.Transient blocking of both B7.1 (CD80) and B7.2 (CD86) in addition to CD40-CD40L interaction fully abrogates the immune response following systemic injection of adenovirus vector.Zoledronic acid, an aminobisphosphonate, modulates differentiation and maturation of human dendritic cells.
P2860
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P2860
B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
B7-1 engagement of cytotoxic T ...... vation in the absence of CD28.
@en
type
label
B7-1 engagement of cytotoxic T ...... vation in the absence of CD28.
@en
prefLabel
B7-1 engagement of cytotoxic T ...... vation in the absence of CD28.
@en
P2093
P2860
P356
P1476
B7-1 engagement of cytotoxic T ...... vation in the absence of CD28.
@en
P2093
F Fallarino
P E Fields
T F Gajewski
P2860
P304
P356
10.1084/JEM.188.1.205
P407
P577
1998-07-01T00:00:00Z